Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria (Q43832680)

27 November 2017

Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria (English)

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27 November 2017

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3

Arthur I Cederbaum

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27 November 2017

Montserrat Marí

1

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PubMed ID

11755319

27 November 2017

Jingxiang Bai

series ordinal

2

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27 November 2017

1 January 2002

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Free Radical Biology and Medicine

27 November 2017

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27 November 2017

32

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27 November 2017

73-83

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27 November 2017

1

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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

27 November 2017

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Superoxide production by the mitochondrial respiratory chain

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial Glutathione: Importance and Transport

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial free radical generation, oxidative stress, and aging

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Transport of glutathione across the mitochondrial membranes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Glutathione depletion induces apoptosis of rat hepatocytes through activation of protein kinase C novel isoforms and dependent increase in AP-1 nuclear binding

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Effect of glutathione depletion and oxidative stress on the in vitro cytotoxicity of velnacrine maleate

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation.

1 reference

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7 January 2021

A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1 reference

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7 January 2021

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against cytochrome P450 2E1-dependent toxicity in HepG2 cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Hydroperoxide metabolism in mammalian organs

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Superoxide anion radical (O2-.), superoxide dismutases, and related matters

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial damage induced by conditions of oxidative stress

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial disease in mouse results in increased oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Pyruvate prevents hydrogen peroxide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Secretion of pyruvate. An antioxidant defense of mammalian cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondria and cell death.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Intracellular ATP, a switch in the decision between apoptosis and necrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Potentiation by chronic ethanol treatment of the mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Lipid hydroperoxide induced mitochondrial dysfunction following acute ethanol intoxication in rats. The critical role for mitochondrial reduced glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Ethanol consumption and liver mitochondria function

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

Ethanol-induced oxidative stress in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900759-6

7 January 2021

10.1016/S0891-5849(01)00759-6

Identifiers

DOI

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27 November 2017

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PubMed ID

11755319