Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism (Q43855742)

27 November 2017

Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism (English)

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27 November 2017

1

Robert L Raffai

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27 November 2017

Karl H Weisgraber

2

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PubMed ID

11792702

27 November 2017

language of work or name

English

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publication date

15 January 2002

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Journal of Biological Chemistry

27 November 2017

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27 November 2017

277

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27 November 2017

11064-11068

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27 November 2017

13

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

27 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Expression of the apolipoprotein E gene in the skin is controlled by a unique downstream enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Apolipoprotein E: far more than a lipid transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Inducible gene targeting in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

Cre recombinase: The universal reagent for genome tailoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111222200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111222200

1 reference

27 November 2017

1 reference

PubMed ID

11792702