Characterization of HIV-1 TAT peptide as an enhancer of HSV-TK/GCV cancer gene therapy (Q43898698)

27 November 2017

title

Characterization of HIV-1 TAT peptide as an enhancer of HSV-TK/GCV cancer gene therapy (English)

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27 November 2017

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O Rautsi

1

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27 November 2017

S Lehmusvaara

2

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27 November 2017

A Ketola

3

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27 November 2017

A-M Määttä

4

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27 November 2017

J Wahlfors

5

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27 November 2017

R Pellinen

6

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27 November 2017

publication date

29 February 2008

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27 November 2017

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27 November 2017

volume

15

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27 November 2017

issue

5

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27 November 2017

page(s)

303-314

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AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

27 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FCGT.2008.17

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2008.17

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2008.17

The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Delivery of bioactive molecules into the cell: the Trojan horse approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

The taming of the cell penetrating domain of the HIV Tat: myths and realities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Characterisation of cell-penetrating peptide-mediated peptide delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Evidence of protein transduction but not intercellular transport by proteins fused to HIV tat in retinal cell culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

TAT-mediated protein transduction into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2008.17

Enhanced secretion and uptake of beta-glucuronidase improves adeno-associated viral-mediated gene therapy of mucopolysaccharidosis type VII mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: implications for gene therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Transcellular transfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Fusion of the human immunodeficiency virus type 1 tat protein transduction domain to thymidine kinase increases bystander effect and induces enhanced tumor killing in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2008.17

Tat8-TK/GCV suicide gene therapy induces pancreatic tumor regression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

HIV-Tat protein transduction domain specifically attenuates growth of polyamine deprived tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Proteoglycan involvement in polyamine uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Inhibition of HIV derived lentiviral production by TAR RNA binding domain of TAT protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

Utility of cell-permeable peptides for enhancement of virus-mediated gene transfer to human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

Herpes simplex virus thymidine kinase-green fluorescent protein fusion gene: new tool for gene transfer studies and gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

HIV-I Tat: a polypeptide for all seasons

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

A third-generation lentivirus vector with a conditional packaging system

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.17

7 January 2021

Identifiers

DOI

10.1038/CGT.2008.17

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Dimensions Publication ID

27 November 2017

1013984750

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