A doxorubicin-CNGRC-peptide conjugate with prodrug properties (Q43930657)

28 November 2017

A doxorubicin-CNGRC-peptide conjugate with prodrug properties (English)

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28 November 2017

Yvette van Hensbergen

1

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28 November 2017

Henk J Broxterman

2

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28 November 2017

Yvonne W Elderkamp

3

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28 November 2017

Jan Lankelma

4

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28 November 2017

Judith C C Beers

5

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28 November 2017

Marc Heijn

6

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28 November 2017

Epie Boven

7

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28 November 2017

Klaas Hoekman

8

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28 November 2017

Herbert M Pinedo

9

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28 November 2017

language of work or name

English

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publication date

1 March 2002

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28 November 2017

Biochemical Pharmacology

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28 November 2017

63

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28 November 2017

5

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28 November 2017

897-908

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Liposomal formulations of anticancer drugs: selectivity and effectiveness

28 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Anticancer drug targets: approaching angiogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Structure and expression of aminopeptidase N.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Anti-cancer activity of targeted pro-apoptotic peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Anti-angiogenesis therapy:concepts and importance of dosing schedules in clinical trials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

New method for the determination of doxorubicin, 4'-epidoxorubicin and all known metabolites in cardiac tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Simple and sensitive quantification of anthracyclines in mouse atrial tissue using high-performance liquid chromatography and fluorescence detection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

CD-13 (‘gp150’; aminopeptidase-N): Co-expression on endothelial and haemopoietic cells with conservation of functional activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Doxorubicin compared with related compounds in a nude mouse model for human ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

The monoclonal antibody ER-BMDM1 recognizes a macrophage and dendritic cell differentiation antigen with aminopeptidase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Peptide-guided cancer drugs show promise in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Direct activation of caspases by RGD-peptides may increase drug sensitivity of tumour cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Synthesis and biological evaluation of 2'-carbamate-linked and 2'-carbonate-linked prodrugs of paclitaxel: selective activation by the tumor-associated protease plasmin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

The antennapedia peptide penetratin translocates across lipid bilayers - the first direct observation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Structure of the human oxytocinase/insulin-regulated aminopeptidase gene and localization to chromosome 5q21

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Bestatin as an experimental tool in mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

Induction of apoptosis by bestatin (ubenimex) in human leukemic cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900928-5

10.1016/S0006-2952(01)00928-5

7 January 2021

Identifiers

DOI

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28 November 2017

1 reference