Intracellular Targets of Paullones. Identification following affinity purification on immobilized inhibitor (Q43966314)

28 November 2017

Intracellular Targets of Paullones. Identification following affinity purification on immobilized inhibitor (English)

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28 November 2017

6

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28 November 2017

Karen M Grant

5

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Laurent Meijer

8

object named as

Laurent Meijer

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28 November 2017

Marie Knockaert

1

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28 November 2017

Karen Wieking

2

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28 November 2017

Sophie Schmitt

3

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28 November 2017

Maryse Leost

4

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28 November 2017

Conrad Kunick

7

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28 November 2017

language of work or name

English

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publication date

18 April 2002

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Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

28

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28 November 2017

25493-25501

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ATP site-directed competitive and irreversible inhibitors of protein kinases

28 November 2017

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Protein kinases as therapeutic targets

21 January 2018

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Inhibition of cyclin-dependent kinases by purine analogues.

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

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Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

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Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

21 January 2018

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Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

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Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

21 January 2018

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Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity

21 January 2018

1 reference

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Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

21 January 2018

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CDK inhibition and cancer therapy

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Cyclin-dependent kinase inhibitors: novel anticancer agents

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Cyclin-dependent kinase inhibitors: useful targets in cell cycle regulation

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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

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3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

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Lithium inhibits glycogen synthase kinase-3 by competition for magnesium.

21 January 2018

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Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

21 January 2018

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Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein

21 January 2018

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Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site

21 January 2018

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The cyclin-dependent kinase (CDK) inhibitor flavopiridol inhibits glycogen phosphorylase

21 January 2018

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The crk3 gene of Leishmania mexicana encodes a stage-regulated cdc2-related histone H1 kinase that associates with p12.

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Sequential dephosphorylation of p34(cdc2) on Thr-14 and Tyr-15 at the prophase/metaphase transition.

21 January 2018

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Purification and properties of Plasmodium falciparum malate dehydrogenase

21 January 2018

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Malate dehydrogenase: a model for structure, evolution, and catalysis

21 January 2018

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Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

21 January 2018

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Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases

21 January 2018

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Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-A resolution

21 January 2018

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Mechanisms of action of flavopiridol

21 January 2018

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Small molecule modulators of cyclin-dependent kinases for cancer therapy

21 January 2018

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Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies

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Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein

21 January 2018

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Potent interaction of flavopiridol with MRP1

21 January 2018

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Tetrameric and dimeric malate dehydrogenase isoenzymes in Trypanosoma cruzi epimastigotes.

21 January 2018

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Trypanosoma brucei: molecular cloning and stage-regulated expression of a malate dehydrogenase localized to the mitochondrion.

21 January 2018

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Molecular cloning of the glycosomal malate dehydrogenase of Trypanosoma brucei.

21 January 2018

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Purification of particulate malate dehydrogenase and phosphoenolpyruvate carboxykinase from Leishmania mexicana mexicana

21 January 2018

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Leishmania mexicana: Subcellular distribution of enzymes in amastigotes and promastigotes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M202651200

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28 November 2017

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