Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease (Q43984158)

28 November 2017

Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease (English)

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28 November 2017

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Scott B Vafai

1

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28 November 2017

Jeffry B Stock

series ordinal

2

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28 November 2017

language of work or name

English

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publication date

1 May 2002

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28 November 2017

4

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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28 November 2017

518

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28 November 2017

1-4

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28 November 2017

1-3

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Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

28 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

The distribution of tau in the mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

A protein factor essential for microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Microtubule-based transport systems in neurons: the roles of kinesins and dyneins

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Defective brain microtubule assembly in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Neurodegenerative tauopathies

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

The effects of aging on gene expression in the hypothalamus and cortex of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

A specific protein carboxyl methylesterase that demethylates phosphoprotein phosphatase 2A in bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Total serum homocysteine in senile dementia of Alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

21 January 2018

Homocysteine metabolism

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Decreased rate of coronary restenosis after lowering of plasma homocysteine levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Alzheimer's disease: genes, proteins, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Hyperhomocysteinemia: an independent risk factor for vascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902702-3

10.1016/S0014-5793(02)02702-3

7 January 2021

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28 November 2017

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24 November 2022

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