Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid (Q43997248)

28 November 2017

Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid (English)

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28 November 2017

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Christine Desmoucelles

1

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28 November 2017

Benoit Pinson

2

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28 November 2017

Christelle Saint-Marc

3

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28 November 2017

Bertrand Daignan-Fornier

4

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28 November 2017

language of work or name

English

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publication date

16 May 2002

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Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

30

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28 November 2017

27036-27044

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Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

28 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M111433200

Proteome analysis and morphological studies reveal multiple effects of the immunosuppressive drug mycophenolic acid specifically resulting from guanylic nucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Mutations in the second largest subunit of RNA polymerase II cause 6-azauracil sensitivity in yeast and increased transcriptional arrest in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Rpb9 subunit of RNA polymerase II binds transcription factor TFIIE and interferes with the SAGA and elongator histone acetyltransferases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111433200

Regulation of an IMP dehydrogenase gene and its overexpression in drug-sensitive transcription elongation mutants of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111433200

Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Identification of a gene for a polyamine transport protein in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Allosteric binding of nucleoside triphosphates to RNA polymerase regulates transcription elongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Saccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Transcriptional regulation of the yeast gmp synthesis pathway by its end products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Mutations sensitizing yeast cells to the start inhibitor nalidixic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111433200

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28 November 2017

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