Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast (Q57371744)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702500%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

title

Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast (English)

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17 October 2019

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C S Hemenway

1

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17 October 2019

J Heitman

series ordinal

2

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17 October 2019

language of work or name

English

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publication date

1 August 1996

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Journal of Biological Chemistry

17 October 2019

published in

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17 October 2019

volume

271

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17 October 2019

issue

31

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17 October 2019

page(s)

18527-18534

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Biochemistry of multidrug resistance mediated by the multidrug transporter

17 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Cyclosporin A and its analogues as modifiers of adriamycin and vincristine resistance in a multi-drug resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Modification of cytotoxic drug resistance by non-immuno-suppressive cyclosporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Overcoming multidrug resistance in Chinese hamster ovary cells in vitro by cyclosporin A (Sandimmune) and non-immunosuppressive derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The mechanism of action of cyclosporin A and FK506

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The a-factor pheromone of Saccharomyces cerevisiae is essential for mating

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Passage of molecules through yeast cell walls: a brief essay-review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Expression of human P-glycoprotein in yeast cells--effects of membrane component sterols on the activity of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Characterization of an exchange reaction between soluble FKBP-12 and the FKBP.ryanodine receptor complex. Modulation by FKBP mutants deficient in peptidyl-prolyl isomerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Differential modulation of P-glycoprotein transport by protein kinase inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Modulation of P-glycoprotein by protein kinase C alpha in a baculovirus expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

P-glycoprotein. Associations between domains and between domains and molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Reversal of multidrug resistance by an immunosuppressive agent FK-506

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Reversion of the P-glycoprotein-mediated multidrug resistance of cancer cells by FK-506 derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.31.18527

21 January 2018

Identifiers

DOI

10.1074/JBC.271.31.18527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702500%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference