Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates (Q44018391)

29 November 2017

title

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates (English)

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29 November 2017

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16

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Severine Chevalley-Maurel

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6

Geert-Jan van Gemert

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Severine Chevalley-Maurel

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Blandine Franke-Fayard

8

Blandine M D Franke-Fayard

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Jean-François Franetich

11

Jean-Francois Franetich

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Chris J Janse

Chris J Janse

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Robert W Sauerwein

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Robert W Sauerwein

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Stephen L Hoffman

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Ivo H J Ploemen

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Cornelus C Hermsen

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1

Takeshi Annoura

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3

Ben C L van Schaijk

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Martijn W Vos

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Audrey Gego

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Dominique Mazier

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Mohammed Sajid

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Severine Chevalley-Maurel

7

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Jean-Francois Franetich

11

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language of work or name

English

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publication date

16 February 2012

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29 November 2017

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volume

30

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issue

16

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page(s)

2662-2670

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Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

29 November 2017

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Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

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That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

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Malaria vaccines: the case for a whole-organism approach

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Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

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Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

7 January 2021

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Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

7 January 2021

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Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

7 January 2021

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Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

7 January 2021

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Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity and cross-protection against heterologous challenge

7 January 2021

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Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells

7 January 2021

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Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites

7 January 2021

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Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells

7 January 2021

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Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites

7 January 2021

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Plasmodium berghei: production and quantitation of hepatic stages derived from irradiated sporozoites in rats and mice.

7 January 2021

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Genetically engineered, attenuated whole-cell vaccine approaches for malaria

7 January 2021

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Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

7 January 2021

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A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development

7 January 2021

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Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

7 January 2021

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Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

7 January 2021

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SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages.

7 January 2021

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Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.

7 January 2021

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Redefining the role of de novo fatty acid synthesis in Plasmodium parasites.

7 January 2021

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Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

7 January 2021

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Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging

7 January 2021

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Structural models for the protein family characterized by gamete surface protein Pfs230 of Plasmodium falciparum

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2012.02.010

Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility

7 January 2021

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Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte

7 January 2021

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Beta-ketoacyl-ACP synthase I/II from Plasmodium falciparum (PfFabB/F)--is it B or F?

7 January 2021

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Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase

7 January 2021

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Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

7 January 2021

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The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2012.02.010

Infectivity-associated changes in the transcriptional repertoire of the malaria parasite sporozoite stage

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2012.02.010

10.1016/J.VACCINE.2012.02.010

7 January 2021

Identifiers

DOI

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29 November 2017

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