ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase (Q44082647)

29 November 2017

ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase (English)

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29 November 2017

Paula B Deming

1

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29 November 2017

Kristina G Flores

2

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29 November 2017

C Stephen Downes

3

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29 November 2017

Richard S Paules

4

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29 November 2017

William K Kaufmann

5

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29 November 2017

language of work or name

English

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publication date

29 July 2002

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Journal of Biological Chemistry

29 November 2017

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29 November 2017

277

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29 November 2017

39

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29 November 2017

36832-36838

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Cell cycle control and cancer

29 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

The human decatenation checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Polo-like kinases: a team that plays throughout mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Polo-like kinases: positive regulators of cell division from start to finish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Purification and cloning of a protein kinase that phosphorylates and activates the polo-like kinase Plx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

MPF localization is controlled by nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Nuclear localization of cyclin B1 controls mitotic entry after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Combinatorial control of cyclin B1 nuclear trafficking through phosphorylation at multiple sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

G1 arrest and cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Chromosome assembly in vitro: Topoisomerase II is required for condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Intra-M phase-promoting factor phosphorylation of cyclin B at the prophase/metaphase transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

Polo-like kinase-1 is a target of the DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206109200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206109200

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release_6rxpkkym7fb27e46qftchjqmga

29 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6rxpkkym7fb27e46qftchjqmga

mapped directly with Wikidata item

24 November 2022

based on heuristic

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