The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets (Q44130861)

30 November 2017

The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets (English)

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30 November 2017

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Sakeneh Zraika

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30 November 2017

Marjorie Dunlop

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2

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30 November 2017

Joseph Proietto

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3

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30 November 2017

Sofianos Andrikopoulos

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4

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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Archives of Biochemistry and Biophysics

30 November 2017

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30 November 2017

405

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30 November 2017

2

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30 November 2017

275-279

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Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

30 November 2017

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Localization of the O-linked N-acetylglucosamine transferase in rat pancreas

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Increased O-GlcNAc transferase in pancreas of rats with streptozotocin-induced diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Glycan-dependent signaling: O-linked N-acetylglucosamine

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Electrophysiology of the pancreatic beta-cell

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Metabolic coupling factors in pancreatic beta-cell signal transduction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

An improved method for isolation of mouse pancreatic islets

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Ether-linked lysophospholipids initiate insulin secretion. Lysophospholipids may mediate effects of phospholipase A2 activation on hormone release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Role of the glucosamine pathway in fat-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

O-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Glycosylation of nucleocytoplasmic proteins: signal transduction and O-GlcNAc

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Immunohistochemical Localization of Cellubrevin on Secretory Granules in Pancreatic B-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Role of syntaxin in mouse pancreatic beta cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Glycosylation sites flank phosphorylation sites on synapsin I: O-linked N-acetylglucosamine residues are localized within domains mediating synapsin I interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Structure of streptozotocin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900397-1

10.1016/S0003-9861(02)00397-1

7 January 2021

Identifiers

DOI

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30 November 2017

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