Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation (Q44207039)

30 November 2017

Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation (English)

1 reference

30 November 2017

4

Hilkka Soininen

1 reference

30 November 2017

Petri Kerokoski

1

1 reference

30 November 2017

Tiina Suuronen

series ordinal

2

1 reference

30 November 2017

Antero Salminen

series ordinal

3

1 reference

30 November 2017

Tuula Pirttilä

series ordinal

5

1 reference

30 November 2017

language of work or name

English

0 references

publication date

1 November 2002

1 reference

Biochemical and Biophysical Research Communications

30 November 2017

1 reference

30 November 2017

298

1 reference

30 November 2017

5

1 reference

30 November 2017

693-698

1 reference

Evidence for cdk5 as a major activity phosphorylating tau protein in porcine brain extract.

30 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Neurotoxicity induces cleavage of p35 to p25 by calpain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Okadaic acid-stimulated degradation of p35, an activator of CDK5, by proteasome in cultured neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Involvement of cyclin dependent kinase5 activator p25 on tau phosphorylation in mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Acute rise in the concentration of free cytoplasmic calcium leads to dephosphorylation of the microtubule-associated protein tau.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

Compromised mitochondrial function results in dephosphorylation of tau through a calcium-dependent process in rat brain cerebral cortical slices.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902543-3

10.1016/S0006-291X(02)02543-3

7 January 2021

Identifiers

DOI

1 reference

30 November 2017

1 reference