Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway (Q44208140)

30 November 2017

title

Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway (English)

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30 November 2017

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3

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30 November 2017

Jessica Pamment

1

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30 November 2017

Eleanor Ramsay

series ordinal

2

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30 November 2017

David Dornan

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4

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30 November 2017

Kathryn L Ball

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5

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30 November 2017

language of work or name

English

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publication date

1 November 2002

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30 November 2017

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30 November 2017

volume

21

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30 November 2017

issue

51

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30 November 2017

page(s)

7776-7785

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205981

30 November 2017

exact match

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cites work

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ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage

21 January 2018

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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

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Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

21 January 2018

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

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Induction of endogenous IFN-alpha and IFN-beta genes by a regulatory transcription factor, IRF-1.

21 January 2018

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Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways

21 January 2018

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Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid

21 January 2018

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Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

21 January 2018

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Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

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Cooperative activity between HER oncogenes and the tumor suppressor IRF-1 results in apoptosis

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Regulation of p53 in response to DNA damage

21 January 2018

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The genetic defect in ataxia-telangiectasia

21 January 2018

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Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts

21 January 2018

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ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

21 January 2018

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A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity

21 January 2018

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

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ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

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Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

21 January 2018

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

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Degradation of transcription factor IRF-1 by the ubiquitin-proteasome pathway. The C-terminal region governs the protein stability

21 January 2018

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Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53.

21 January 2018

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Common deleted region on the long arm of chromosome 5 in esophageal carcinoma.

21 January 2018

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The ATM protein is required for sustained activation of NF-kappaB following DNA damage

21 January 2018

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ATM: genome stability, neuronal development, and cancer cross paths

21 January 2018

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Heightened induction of c-jun mRNA by PMA, EGF and IL-1 in ataxia telangiectasia lymphoblasts

21 January 2018

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Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Constitutive expression of the cyclin-dependent kinase inhibitor p21 is transcriptionally regulated by the tumor suppressor protein p53.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Regulation of interferon-beta gene: structure and function of cis-elements and trans-acting factors

21 January 2018

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IRF family of transcription factors as regulators of host defense

21 January 2018

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Activation of IFN-beta element by IRF-1 requires a posttranslational event in addition to IRF-1 synthesis

21 January 2018

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Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia

21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Recombinant ATM protein complements the cellular A-T phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Activation and repression of the 2-5A synthetase and p21 gene promoters by IRF-1 and IRF-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Interferon regulatory factor 1 tryptophan 11 to arginine point mutation abolishes DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

RB protein as a cellular "corral" for growth-promoting proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Altered DNA repair and dysregulation of p53 in IRF-1 null hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

The transcription factor interferon regulatory factor-1 is expressed during both early G1 and the G1/S transition in the prolactin-induced lymphocyte cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Multiple prolactin-responsive elements mediate G1 and S phase expression of the interferon regulatory factor-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

IRF-1: the transcription factor linking the interferon response and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Maximal induction of p69 2', 5'-oligoadenylate synthetase in Daudi cells requires cooperation between an ISRE and two IRF-1-like elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205981

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205981

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Dimensions Publication ID

30 November 2017

1002984449

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1 reference