Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein (Q44225651)

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English	Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 December 2017

Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

Alzheimer's disease

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inferred from title

toxic encephalopathy

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5

object named as

Yoo-Hun Suh

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Europe PubMed Central

PubMed publication ID

1 December 2017

author name string

Young Hae Chong

1

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Europe PubMed Central

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1 December 2017

Soon Ah Shin

2

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Europe PubMed Central

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1 December 2017

Hyun Joo Lee

3

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Europe PubMed Central

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1 December 2017

Ji Hee Lee Kang

4

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Europe PubMed Central

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1 December 2017

publication date

1 December 2002

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Europe PubMed Central

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1 December 2017

Journal of Neuroimmunology

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Europe PubMed Central

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1 December 2017

133

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Europe PubMed Central

PubMed publication ID

1 December 2017

1-2

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Europe PubMed Central

PubMed publication ID

1 December 2017

160-174

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Europe PubMed Central

PubMed publication ID

1 December 2017

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

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Inflammation and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro.

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7 January 2021

based on heuristic

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Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein

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7 January 2021

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Does IFNgamma play a role in neurodegeneration?

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7 January 2021

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Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.

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7 January 2021

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Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease.

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A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

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7 January 2021

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Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Catecholamines inhibit microglial nitric oxide production

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7 January 2021

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Effect of a carboxy-terminal fragment of the Alzheimer's amyloid precursor protein on expression of proinflammatory cytokines in rat glial cells

1 reference

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7 January 2021

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Effects of the beta-amyloid and carboxyl-terminal fragment of Alzheimer's amyloid precursor protein on the production of the tumor necrosis factor-alpha and matrix metalloproteinase-9 by human monocytic THP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Neurotoxic APP C-terminal and β-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Suppression of astroglial nitric oxide synthase expression by norepinephrine results from decreased NOS-2 promoter activity

1 reference

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7 January 2021

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NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease

1 reference

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7 January 2021

based on heuristic

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Membrane currents induced in Xenopus oocytes by the C-terminal fragment of the beta-amyloid precursor protein

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7 January 2021

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Norepinephrine increases I kappa B alpha expression in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Disease-specific patterns of locus coeruleus cell loss

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Evidence for an interferon-related inflammatory reaction in the trisomy 16 mouse brain leading to caspase-1-mediated neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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IFNgamma enhances microglial reactions to hippocampal axonal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Neurotoxicity of a carboxyl-terminal fragment of the Alzheimer's amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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The neurotoxic carboxy-terminal fragment of the Alzheimer amyloid precursor binds specifically to a neuronal cell surface molecule: pH dependence of the neurotoxicity and the binding

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor rece

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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APP carboxyl-terminal fragment without or with abeta domain equally induces cytotoxicity in differentiated PC12 cells and cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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A betaPP peptide carboxyl-terminal to Abeta is neurotoxic

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered processing characteristics of beta-amyloid-containing peptides in cytosol and in media of familial Alzheimer's disease cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Roles of nuclear factor kappaB in neuronal survival and plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

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7 January 2021

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Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Activation of microglial cells by beta-amyloid protein and interferon-gamma.

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Decrease in adenylate cyclase activity antecedes neurofibrillary tangle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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G-protein coupled signal transduction systems in the Alzheimer's disease brain

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7 January 2021

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Evaluation of nitrite production by human monocyte-derived macrophages

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Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

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7 January 2021

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Effects of carboxyl-terminal fragment of Alzheimer's amyloid precursor protein and amyloid beta-peptide on the production of cytokines and nitric oxide in glial cells

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

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7 January 2021

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Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: genes, proteins, and therapy

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophage and microglial responses to cytokines in vitro: phagocytic activity, proteolytic enzyme release, and free radical production

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hemorheological changes and overproduction of cytokines from immune cells in mild to moderate dementia of the Alzheimer's type: adverse effects on cerebromicrovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Behavioral and neuropathologic changes induced by central injection of carboxyl-terminal fragment of beta-amyloid precursor protein in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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An etiological role of amyloidogenic carboxyl-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Serum levels of gamma interferon in patients with Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Age- and concentration-dependent neuroprotection and toxicity by TNF in cortical neurons from beta-amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hippocampal level of neural specific adenylyl cyclase type I is decreased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CREB and the formation of long-term memory

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons

1 reference

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7 January 2021

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Identifiers

10.1016/S0165-5728(02)00349-1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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