Benzo(c)quinolizinium drugs inhibit degradation of Delta F508-CFTR cytoplasmic domain. (Q44263795)

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16 December 2019

title

Benzo(c)quinolizinium drugs inhibit degradation of Delta F508-CFTR cytoplasmic domain (English)

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16 December 2019

3

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16 December 2019

author name string

Fiona L L Stratford

1

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16 December 2019

Malcolm M C Pereira

2

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16 December 2019

Margaret A McPherson

4

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16 December 2019

Robert L Dormer

5

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16 December 2019

language of work or name

English

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publication date

1 January 2003

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Biochemical and Biophysical Research Communications

16 December 2019

published in

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16 December 2019

volume

300

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16 December 2019

issue

2

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16 December 2019

page(s)

524-530

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

16 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Identification of the cystic fibrosis gene: genetic analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Abnormal localization of cystic fibrosis transmembrane conductance regulator in primary cultures of cystic fibrosis airway epithelia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Development of substituted Benzo[c]quinolizinium compounds as novel activators of the cystic fibrosis chloride channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Degradation of CFTR by the ubiquitin-proteasome pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Evidence that endoplasmic reticulum (ER)-associated degradation of cystic fibrosis transmembrane conductance regulator is linked to retrograde translocation from the ER membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

A principal role for the proteasome in endoplasmic reticulum-associated degradation of misfolded intracellular cystic fibrosis transmembrane conductance regulator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

An antibody against a cftr-derived synthetic peptide, incorporated into living submandibular cells, inhibits beta-adrenergic stimulation of mucin secretion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Actions of adenosine A1 and A2 receptor antagonists on CFTR antibody-inhibited beta-adrenergic mucin secretion response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Nucleotidase activities of the 26 S proteasome and its regulatory complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Cotranslational ubiquitination of cystic fibrosis transmembrane conductance regulator in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

A possible role of ER-60 protease in the degradation of misfolded proteins in the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Quality control by proteases in the endoplasmic reticulum. Removal of a protease-sensitive site enhances expression of human P-glycoprotein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

Altered protein folding may be the molecular basis of most cases of cystic fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902883-8

10.1016/S0006-291X(02)02883-8

7 January 2021

Identifiers

DOI

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16 December 2019

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