PKC-θ exists in an oxidized inactive form in naive human T cells. (Q44271851)

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24 February 2020

title

PKC-θ exists in an oxidized inactive form in naive human T cells (English)

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24 February 2020

7

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24 February 2020

Charlotte Menné Bonefeld

10

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24 February 2020

Carsten Geisler

11

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24 February 2020

Marina von Essen

1

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24 February 2020

Martin Kongsbak

2

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24 February 2020

5

Lasse Boding

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24 February 2020

3

Trine Bøegh Levring

1 reference

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24 February 2020

4

Ann Kathrine Hansen

1 reference

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Jens Peter Holst Lauritsen

24 February 2020

6

object named as

Jens Peter Holst Lauritsen

1 reference

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8

Gottfried Baier

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24 February 2020

author name string

Niels Ødum

9

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24 February 2020

language of work or name

English

0 references

publication date

12 April 2013

1 reference

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European Journal of Immunology

24 February 2020

published in

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24 February 2020

volume

43

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issue

6

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24 February 2020

page(s)

1659-1666

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

24 February 2020

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Involvement of distinct PKC gene products in T cell functions

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Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

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Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation

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Molecular characterization of the di-leucine-based internalization motif of the T cell receptor

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Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes.

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The Phosphorylation State of CD3γ Influences T Cell Responsiveness and Controls T Cell Receptor Cycling

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The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

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Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

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TCR down-regulation controls virus-specific CD8+ T cell responses

21 January 2018

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TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

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TCR down-regulation controls T cell homeostasis.

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Vitamin D controls T cell antigen receptor signaling and activation of human T cells

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Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes

21 January 2018

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Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens

21 January 2018

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Extracellular redox modulation by regulatory T cells

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Protein kinase C signaling and oxidative stress

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Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells

21 January 2018

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Covalent modification of protein kinase C isozymes by the inactivating peptide substrate analog N-biotinyl-Arg-Arg-Arg-Cys-Leu-Arg-Arg-Leu. Evidence that the biotinylated peptide is an active-site affinity label

21 January 2018

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Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology

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Redox remodeling as an immunoregulatory strategy

21 January 2018

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21 January 2018

Thioredoxin reductase

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The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

21 January 2018

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Thioredoxin restores nitric oxide-induced inhibition of protein kinase C activity in lung endothelial cells

21 January 2018

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S-nitrosylation Inhibits Protein Kinase C–mediated Contraction in Mouse Aorta

21 January 2018

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CD3 antigen-mediated calcium signals and protein kinase C activation are higher in CD45R0+ than in CD45RA+ human T lymphocyte subsets

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Signaling control of memory T cell generation and function

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Activated human CD4+ T cells express transporters for both cysteine and cystine

21 January 2018

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21 January 2018

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21 January 2018

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T Cell Receptor ζ Allows Stable Expression of Receptors Containing the CD3γ Leucine-based Receptor-sorting Motif

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Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

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PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation

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inferred from DOI database lookup

7 January 2021

based on heuristic

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJI.201243140

1 reference

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24 February 2020

1 reference