Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease (Q44297954)

1 December 2017

Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease (English)

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1 December 2017

Vasily N Dobrovolsky

1

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1 December 2017

Thomas Bucci

2

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1 December 2017

Robert H Heflich

3

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1 December 2017

John Desjardins

4

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1 December 2017

Frank C Richardson

5

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1 December 2017

1 January 2003

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Molecular Genetics and Metabolism

1 December 2017

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1 December 2017

78

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1 December 2017

1-10

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1 December 2017

1

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A mutational assay system using the thymidine kinase locus in mouse lymphoma cells

1 December 2017

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Genomic cloning and preliminary characterization of the human thymidine kinase gene

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11,

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Human Thymidine Kinase Gene Locus: Assignment to Chromosome 17 in a Hybrid of Man and Mouse Cells

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Localization of the mouse thymidine kinase gene to the distal portion of chromosome 11.

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Synteny of the genes for thymidine kinase and galactokinase in the mouse and their assignment to mouse chromosome 11

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Regulation and biological function of thymidine kinase

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Cloning of mouse mitochondrial thymidine kinase 2 cDNA

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Thymidine kinases: the enzymes and their clinical usefulness

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Viral thymidine kinases and their relatives

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Role of Herpes simplex Virus Thymidine Kinase Expression in Viral Pathogenesis and Latency

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Mitochondrial DNA depletion: mutations in thymidine kinase gene with myopathy and SMA.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

The role of folic acid and Vitamin B12 in genomic stability of human cells

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Folic acid deficiency and cancer: mechanisms of DNA instability

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Development of a novel mouse tk+/- embryonic stem cell line for use in mutagenicity studies

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Tk+/- mouse model for detecting in vivo mutation in an endogenous, autosomal gene

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

7,12-dimethylbenz[a]anthracene-induced mutation in the Tk gene of Tk(+/-) mice: automated scoring of lymphocyte clones using a fluorescent viability indicator.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Expression of thymidine kinase variants is a function of the replicative state of cells

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

A review of the molecular basis of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Human adenine phosphoribosyltransferase deficiency. Demonstration of a single mutant allele common to the Japanese

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Increased cell killing and mutagenecity by DNA alkylating agents in cells with decreased TTP pools

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Thymidine kinase deficient cells with decreased TTP pools are hypersensitive to DNA alkylating agents

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Different effect of thymidine kinase loss on TTP pools; comparison among human leukemia cell lines

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Pulmonary manifestations of Goodpasture's syndrome. Antiglomerular basement membrane disease and related disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Contribution of de-novo and salvage synthesis to the uracil nucleotide pool in mouse tissues and tumors in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Germ and somatic cell abnormalities following in vivo administration of thymidine and adenine

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Male–female differences in fertility and blood pressure in ACE-deficient mice

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

Angiotensin-converting enzyme and male fertility

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https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900224-X

7 January 2021

10.1016/S1096-7192(02)00224-X

Identifiers

DOI

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1 December 2017

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