Mutational analysis of plasminogen activator inhibitor-1. (Q44402632)

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2 November 2019

title

Mutational analysis of plasminogen activator inhibitor-1 (English)

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2 November 2019

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3

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2 November 2019

author name string

Troels Wind

1

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2 November 2019

Jan K Jensen

2

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2 November 2019

Paulina Kulig

4

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2 November 2019

Peter A Andreasen

5

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2 November 2019

language of work or name

English

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publication date

1 April 2003

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2 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694181%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

270

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2 November 2019

issue

8

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2 November 2019

page(s)

1680-1688

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Structure of a serpin-protease complex shows inhibition by deformation

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Serpins and other covalent protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Structural basis of latency in plasminogen activator inhibitor-1

21 January 2018

1 reference

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Mutations which impede loop/sheet polymerization enhance the secretion of human alpha 1-antitrypsin deficiency variants.

21 January 2018

1 reference

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Latent alpha1-antichymotrypsin. A molecular explanation for the inactivation of alpha1-antichymotrypsin in chronic bronchitis and emphysema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Structures of active and latent PAI-1: a possible stabilizing role for chloride ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Different structural requirements for plasminogen activator inhibitor 1 (PAI-1) during latency transition and proteinase inhibition as evidenced by phage-displayed hypermutated PAI-1 libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Mechanisms of conversion of plasminogen activator inhibitor 1 from a suicide inhibitor to a substrate by monoclonal antibodies

21 January 2018

1 reference

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Epitope mapping for four monoclonal antibodies against human plasminogen activator inhibitor type-1: implications for antibody-mediated PAI-1-neutralization and vitronectin-binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

The F-helix of serpins plays an essential, active role in the proteinase inhibition mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

The biostructural pathology of the serpins: critical function of sheet opening mechanism

21 January 2018

1 reference

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Sequence-specific binding of the N-terminal three-finger fragment of Xenopus transcription factor IIIA to the internal control region of a 5S RNA gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Plasminogen activator inhibitor type-1: reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site

21 January 2018

1 reference

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Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

21 January 2018

1 reference

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The role of beta-strand 5A of plasminogen activator inhibitor-1 in regulation of its latency transition and inhibitory activity by vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

Probing the role of the F-helix in serpin stability through a single tryptophan substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03524.X

10.1046/J.1432-1033.2003.03524.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12694181%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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