Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells (Q44466998)

3 December 2017

title

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells (English)

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3 December 2017

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endoplasmic reticulum

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author name string

Cook DG

1

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3 December 2017

Forman MS

2

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3 December 2017

Sung JC

3

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3 December 2017

Leight S

4

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3 December 2017

Kolson DL

5

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3 December 2017

Iwatsubo T

6

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3 December 2017

Lee VM

7

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3 December 2017

Doms RW

8

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3 December 2017

language of work or name

English

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publication date

1 September 1997

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3 December 2017

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3 December 2017

volume

3

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3 December 2017

issue

9

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3 December 2017

page(s)

1021-1023

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https://scigraph.springernature.com/pub.10.1038/nm0997-1021

3 December 2017

exact match

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cites work

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

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7 January 2021

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

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Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

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7 January 2021

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons.

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7 January 2021

Pre- and post-Golgi vacuoles operate in the transport of Semliki Forest virus membrane glycoproteins to the cell surface

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7 January 2021

Inhibition of beta-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

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7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

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7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

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Light and electron microscopic localization of presenilin-1 in primate brain.

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7 January 2021

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

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7 January 2021

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

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7 January 2021

Expression of foreign proteins in a human neuronal system

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7 January 2021

Identifiers

DOI

10.1038/NM0997-1021

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3 December 2017

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