p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity. (Q44548784)

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6 November 2019

title

p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity (English)

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6 November 2019

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Yan Zhang

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Yanguo Hong

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Younes Bounhar

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Megan Blacker

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Xavier Roucou

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Omar Tounekti

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Emily Vereker

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William J Bowers

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Howard J Federoff

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Cynthia G Goodyer

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Andrea LeBlanc

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6 November 2019

language of work or name

English

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publication date

1 August 2003

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6 November 2019

published in

Journal of Neuroscience

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6 November 2019

volume

23

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issue

19

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6 November 2019

page(s)

7385-7394

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Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

6 November 2019

cites work

1 reference

12 December 2020

p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure

1 reference

12 December 2020

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease.

1 reference

12 December 2020

P75 neurotrophin receptor in the nucleus basalis of meynert in relation to age, sex, and Alzheimer's disease

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12 December 2020

Nerve growth factor activation of nuclear factor kappaB through its p75 receptor is an anti-apoptotic signal in RN22 schwannoma cells

1 reference

12 December 2020

beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

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12 December 2020

Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration

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12 December 2020

Neurotrophins induce death of hippocampal neurons via the p75 receptor

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12 December 2020

Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8.

1 reference

12 December 2020

Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat

1 reference

12 December 2020

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

1 reference

12 December 2020

The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway

1 reference

12 December 2020

Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers

1 reference

12 December 2020

Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid.

1 reference

12 December 2020

Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo

1 reference

12 December 2020

A novel p75NTR signaling pathway promotes survival, not death, of immunopurified neocortical subplate neurons

1 reference

12 December 2020

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

1 reference

12 December 2020

A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2

1 reference

12 December 2020

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

1 reference

12 December 2020

Prion protein protects human neurons against Bax-mediated apoptosis

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12 December 2020

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

12 December 2020

Neurotrophin signalling pathways regulating neuronal apoptosis

1 reference

12 December 2020

Regulation of cell survival by secreted proneurotrophins

1 reference

12 December 2020

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

1 reference

12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

1 reference

12 December 2020

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

1 reference

12 December 2020

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

1 reference

12 December 2020

Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.

1 reference

12 December 2020

Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.

1 reference

12 December 2020

Role of p75 neurotrophin receptor in the neurotoxicity by beta-amyloid peptides and synergistic effect of inflammatory cytokines

1 reference

12 December 2020

p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones.

1 reference

12 December 2020

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

1 reference

12 December 2020

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

1 reference

12 December 2020

Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease

1 reference

12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

12 December 2020

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

1 reference

12 December 2020

An efficient deletion mutant packaging system for defective herpes simplex virus vectors: potential applications to human gene therapy and neuronal physiology.

1 reference

12 December 2020

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

1 reference

12 December 2020

Expression and structure of the human NGF receptor

1 reference

12 December 2020

Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide

1 reference

12 December 2020

Expression of the low-affinity nerve growth factor receptor enhances beta-amyloid peptide toxicity

1 reference

12 December 2020

Amyloid beta protein levels in cerebrospinal fluid are elevated in early-onset Alzheimer's disease

1 reference

12 December 2020

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

1 reference

12 December 2020

Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor

1 reference

12 December 2020

The functional characteristics of Schwann cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve

1 reference

12 December 2020

Induction of apoptosis by the low-affinity NGF receptor

1 reference

12 December 2020

Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

1 reference

12 December 2020

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

1 reference

12 December 2020

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

1 reference

12 December 2020

A molecular mechanism for the effect of lithium on development

1 reference

12 December 2020

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

12 December 2020

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

1 reference

12 December 2020

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

12 December 2020

Processing of amyloid precursor protein in human primary neuron and astrocyte cultures.

1 reference

12 December 2020

p75NTR and apoptosis: Trk-dependent and Trk-independent effects

1 reference

12 December 2020

Signalling through the neurotrophin receptor p75NTR.

1 reference

12 December 2020

Biochemical characteristics of caspases-3, -6, -7, and -8

1 reference

12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

1 reference

12 December 2020

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

1 reference

12 December 2020

Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells

1 reference

12 December 2020

10.1523/JNEUROSCI.23-19-07385.2003

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917374%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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6 November 2019

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