Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. (Q44572995)

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7 November 2019

title

Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant (English)

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7 November 2019

author name string

Geoffrey S Findlay

1

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7 November 2019

Rachel Phelan

2

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7 November 2019

Michael T Roberts

3

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7 November 2019

Gregg E Homanics

4

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7 November 2019

Susan E Bergeson

5

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7 November 2019

Gregory F Lopreato

6

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7 November 2019

S John Mihic

7

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7 November 2019

Yuri A Blednov

8

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7 November 2019

R Adron Harris

9

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7 November 2019

language of work or name

English

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publication date

1 September 2003

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7 November 2019

published in

Journal of Neuroscience

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7 November 2019

volume

23

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7 November 2019

issue

22

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7 November 2019

page(s)

8051-8059

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Stable expression of human glycine alpha1 and alpha2 homomeric receptors in mouse L(tk-) cells

7 November 2019

cites work

1 reference

12 December 2020

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

12 December 2020

Glycine and gamma-aminobutyric acid(A) receptor function is enhanced by inhaled drugs of abuse.

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12 December 2020

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

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12 December 2020

Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

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12 December 2020

Molecular and neuronal substrate for the selective attenuation of anxiety.

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12 December 2020

The anesthetic potency of propanol and butanol versus propanethiol and butanethiol in alpha1 wild type and alpha1(S267Q) glycine receptors

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12 December 2020

Molecular targets for the myorelaxant action of diazepam.

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12 December 2020

Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors

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12 December 2020

Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn.

1 reference

12 December 2020

Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells

1 reference

12 December 2020

Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice

1 reference

12 December 2020

Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations

1 reference

12 December 2020

Disease-specific human glycine receptor alpha1 subunit causes hyperekplexia phenotype and impaired glycine- and GABA(A)-receptor transmission in transgenic mice.

1 reference

12 December 2020

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain

1 reference

12 December 2020

Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound

1 reference

12 December 2020

NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating

1 reference

12 December 2020

Molecular modelling of specific and non-specific anaesthetic interactions

1 reference

12 December 2020

Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice

1 reference

12 December 2020

Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?

1 reference

12 December 2020

GABA(A) receptor beta3 subunit deletion decreases alpha2/3 subunits and IPSC duration

1 reference

12 December 2020

Isoform-selective deficit of glycine receptors in the mouse mutant spastic

1 reference

12 December 2020

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain

1 reference

12 December 2020

Changes in benzodiazepine receptor binding as seen autoradiographically in the central nervous system of the spastic mouse

1 reference

12 December 2020

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

12 December 2020

Glycine receptor alteration in the mutant mouse spastic

1 reference

12 December 2020

Identification of a gephyrin binding motif on the glycine receptor beta subunit

1 reference

12 December 2020

The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex

1 reference

12 December 2020

The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton

1 reference

12 December 2020

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists

1 reference

12 December 2020

A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death

1 reference

12 December 2020

A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse

1 reference

12 December 2020

Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.

1 reference

12 December 2020

The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 element

1 reference

12 December 2020

Point mutation of glycine receptor alpha 1 subunit in the spasmodic mouse affects agonist responses

1 reference

12 December 2020

Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

1 reference

12 December 2020

A novel mutation (Gln266-->His) in the alpha 1 subunit of the inhibitory glycine-receptor gene (GLRA1) in hereditary hyperekplexia

1 reference

12 December 2020

Low level expression of glycine receptor beta subunit transgene is sufficient for phenotype correction in spastic mice

1 reference

12 December 2020

Measurement of glycine receptor function by radioactive chloride uptake

1 reference

12 December 2020

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

1 reference

12 December 2020

Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics

1 reference

12 December 2020

The frameshift mutation oscillator (Glra1(spd-ot)) produces a complete loss of glycine receptor alpha1-polypeptide in mouse central nervous system

1 reference

12 December 2020

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

1 reference

12 December 2020

Inbred mouse strains differ in the regulation of startle and prepulse inhibition of the startle response.

1 reference

12 December 2020

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

1 reference

12 December 2020

Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes

1 reference

12 December 2020

The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating

1 reference

12 December 2020

10.1523/JNEUROSCI.23-22-08051.2003

Identifiers

DOI

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7 November 2019

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7 November 2019

PubMed publication ID

12954867

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