The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes (Q44605310)

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scientific article published on October 1, 2003

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English	The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes	scientific article published on October 1, 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 December 2017

The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes (English)

1 reference

10.1523/JNEUROSCI.23-26-08949.2003

https://api.crossref.org/works/10.1523/JNEUROSCI.23-26-08949.2003

17 March 2024

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2

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Laura L Dugan

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

author name string

Biplab Dasgupta

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

David H. Gutmann

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

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publication date

1 October 2003

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Europe PubMed Central

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4 December 2017

full work available at URL

https://www.jneurosci.org/content/jneuro/23/26/8949.full.pdf

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

http://www.jneurosci.org/cgi/content/abstract/23/26/8949

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

https://europepmc.org/articles/PMC6740397

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

https://europepmc.org/articles/PMC6740397?pdf=render

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

https://doi.org/10.1523/jneurosci.23-26-08949.2003

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523097

17 March 2024

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.23-26-08949.2003

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10.1523/JNEUROSCI.23-26-08949.2003

https://api.crossref.org/works/10.1523/JNEUROSCI.23-26-08949.2003

17 March 2024

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

26

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

8949-8954

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

Differential effects of cAMP in neurons and astrocytes. Role of B-raf

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracranial gliomas in neurofibromatosis type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase-activating polypeptide induces astrocyte differentiation of precursor cells from developing cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Rap1 GTPase in astrocyte growth regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurofibromatosis type 1 gene encodes a protein related to GAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes are one of the main target cells for pituitary adenylate cyclase-activating polypeptide in the central nervous system. Astrocytes are very heterogeneous regarding both basal movement of intracellular free calcium ([Ca2+]i) and the [Ca2+]i

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural tube expression of pituitary adenylate cyclase-activating peptide (PACAP) and receptor: potential role in patterning and neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14523097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-26-08949.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740397&resulttype=core&format=json

12 May 2020

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