Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver (Q44652923)

5 December 2017

Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver (English)

1 reference

5 December 2017

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1 reference

https://api.crossref.org/works/10.1016/S0041-008X(03)00338-7

31 March 2024

author name string

Noé Galván

1

1 reference

5 December 2017

Renata Jaskula-Sztul

2

1 reference

5 December 2017

Peter S. MacWilliams

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14613719

31 March 2024

Charles J. Czuprynski

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14613719

31 March 2024

Colin R. Jefcoate

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14613719

31 March 2024

language of work or name

English

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National Center for Biotechnology Information

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31 March 2024

publication date

1 November 2003

1 reference

5 December 2017

15 November 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14613719

full work available at URL

31 March 2024

https://api.elsevier.com/content/article/PII:S0041008X03003387?httpAccept=text/xml

1 reference

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31 March 2024

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https://api.crossref.org/works/10.1016/S0041-008X(03)00338-7

Toxicology and Applied Pharmacology

31 March 2024

published in

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5 December 2017

193

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1

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5 December 2017

84-96

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Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets

5 December 2017

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7 January 2021

Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation

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7 January 2021

Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes

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7 January 2021

CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity

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7 January 2021

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

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7 January 2021

Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells

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7 January 2021

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes

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7 January 2021

The aryl hydrocarbon receptor complex

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7 January 2021

Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis

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7 January 2021

Bone marrow stromal cells constitutively express high levels of cytochrome P4501B1 that metabolize 7,12-dimethylbenz[a]anthracene.

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7 January 2021

Regulation of genes encoding NAD(P)H:quinone oxidoreductases

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7 January 2021

Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by alpha-naphthoflavone

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7 January 2021

Bone marrow toxicity induced by oral benzo[a]pyrene: protection resides at the level of the intestine and liver

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7 January 2021

Oxidative Metabolism of Polycyclic Aromatic Hydrocarbons to Ultimate Carcinogens

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7 January 2021

Induction of immunotoxicity by polycyclic hydrocarbons: role of the Ah locus.

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7 January 2021

Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene

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7 January 2021

Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons

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7 January 2021

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

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7 January 2021

Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate ge

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7 January 2021

In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues

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7 January 2021

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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7 January 2021

Regulation of preB cell apoptosis by aryl hydrocarbon receptor/transcription factor-expressing stromal/adherent cells

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7 January 2021

Drug-metabolizing enzymes, polymorphisms and interindividual response to environmental toxicants

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7 January 2021

7,12-Dimethylbenz[a]anthracene-Induced Bone Marrow Toxicity Is p53-Dependent

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7 January 2021

7,12-Dimethylbenz[a]anthracene induces apoptosis in murine pre-B cells through a caspase-8-dependent pathway

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7 January 2021

Dihydrodiol dehydrogenase and its role in polycyclic aromatic hydrocarbon metabolism

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7 January 2021

Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2

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7 January 2021

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions

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7 January 2021

Aryl hydrocarbon receptor-mediated signal transduction

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7 January 2021

Mouse endometrium stromal cells express a polycyclic aromatic hydrocarbon-inducible cytochrome P450 that closely resembles the novel P450 in mouse embryo fibroblasts (P450EF).

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7 January 2021

Ah receptor signaling pathways

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7 January 2021

Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene

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7 January 2021

The murine Ah locus: in utero toxicity and teratogenesis associated with genetic differences in benzo[a]pyrene metabolism

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7 January 2021

The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

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7 January 2021

Immunosuppression following 7,12-dimethylbenz[a]anthracene exposure in B6C3F1 mice. I. Effects on humoral immunity and host resistance.

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7 January 2021

Immunosuppression by polycyclic aromatic hydrocarbons: a structure-activity relationship in B6C3F1 and DBA/2 mice.

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7 January 2021

Induction of cytochrome P4501A1.

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7 January 2021

Binding and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene by seven purified forms of cytochrome P-450.

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7 January 2021

Induction of PreB cell apoptosis by 7,12-dimethylbenz[a]anthracene in long-term primary murine bone marrow cultures

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7 January 2021

Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B

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7 January 2021

Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene

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Quantitative analysis of constitutive and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cytochrome P450 1B1 expression in human lymphocytes

31 March 2024

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31 March 2024

Identifiers

1 reference

5 December 2017

1 reference