Expression of Glutamate Decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy. (Q44661939)

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6 March 2020

title

Expression of Glutamate Decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy (English)

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6 March 2020

4

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author name string

Renata Leke

series ordinal

1

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6 March 2020

Themis R Silveira

series ordinal

2

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6 March 2020

Thayssa D C Escobar

series ordinal

3

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6 March 2020

publication date

1 August 2013

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6 March 2020

published in

Neurochemical Research

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6 March 2020

volume

39

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issue

3

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6 March 2020

page(s)

605-611

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https://scigraph.springernature.com/pub.10.1007/s11064-013-1116-y

6 March 2020

exact match

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cites work

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Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome.

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Potential mechanisms of enhanced GABA-mediated inhibitory neurotransmission in liver failure

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Expression of gamma-aminobutyric acid A receptor subunits alpha1, beta1, gamma2 mRNA in rats with hepatic encephalopathy

21 January 2018

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Motor activity is modulated via different neuronal circuits in rats with chronic liver failure than in normal rats.

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Enhanced GABA release in cerebral cortical slices derived from rats with thioacetamide-induced hepatic encephalopathy

21 January 2018

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Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy

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Does ammonia contribute to increased GABA-ergic neurotransmission in liver failure?

21 January 2018

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Two genes encode distinct glutamate decarboxylases

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Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions.

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The role of the synthetic enzyme GAD65 in the control of neuronal gamma-aminobutyric acid release

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Regulation of gamma-aminobutyric acid synthesis in the brain

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GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity

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Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine

21 January 2018

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Metabolic distinction between vesicular and cytosolic GABA in cultured GABAergic neurons using 13C magnetic resonance spectroscopy

21 January 2018

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The pathophysiology of biliary obstruction and its effect on phagocytic and immune function

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Expression of GAD65 and GAD67 immunoreactivity in MPTP-treated monkeys with or without L-DOPA administration

21 January 2018

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Acute changes in the neuronal expression of GABA and glutamate decarboxylase isoforms in the rat piriform cortex following status epilepticus

21 January 2018

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Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

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Post-translational regulation of L-glutamic acid decarboxylase in the brain

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Transcriptional control of Gad2

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Kinetic differences between the isoforms of glutamate decarboxylase: implications for the regulation of GABA synthesis

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Role of synaptic vesicle proton gradient and protein phosphorylation on ATP-mediated activation of membrane-associated brain glutamate decarboxylase.

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Protein phosphorylation of human brain glutamic acid decarboxylase (GAD)65 and GAD67 and its physiological implications

21 January 2018

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Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alpha

21 January 2018

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Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters.

21 January 2018

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A palmitoylation cycle dynamically regulates partitioning of the GABA-synthesizing enzyme GAD65 between ER-Golgi and post-Golgi membranes

21 January 2018

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Activity-dependent cleavage of brain glutamic acid decarboxylase 65 by calpain.

21 January 2018

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Distinct protein forms are produced from alternatively spliced bicistronic glutamic acid decarboxylase mRNAs during development

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Metabolism and brain uptake of gamma-aminobutyric acid in galactosamine-induced hepatic encephalopathy in rats.

21 January 2018

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Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine.

21 January 2018

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Metabolic compartmentation of glutamate associated with the formation of gamma-aminobutyrate

21 January 2018

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Localization of cells preferentially expressing GAD(67) with negligible GAD(65) transcripts in the rat hippocampus. A double in situ hybridization study.

21 January 2018

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The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

21 January 2018

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Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy

21 January 2018

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12 December 2020

The GABA hypothesis of the pathogenesis of hepatic encephalopathy: current status

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12 December 2020

Changes in glutamate-cycle enzyme mRNA levels in a rat model of hepatic encephalopathy

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12 December 2020

Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain

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12 December 2020

Changes in the metabolism and binding of GABA in the rat brain in thioacetamide-induced hepatogenic encephalopathy.

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12 December 2020

Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms

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12 December 2020

Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

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12 December 2020

Loss of GABAB binding sites in the cerebral cortex of rats with acute hepatic encephalopathy

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12 December 2020

Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U-13C]glutamate

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12 December 2020

Glutamate and glutamine metabolism in cultured GABAergic neurons studied by 13C NMR spectroscopy may indicate compartmentation and mitochondrial heterogeneity

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12 December 2020

10.1007/S11064-013-1116-Y

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904086%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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