Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes (Q44664692)

5 December 2017

Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes (English)

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5 December 2017

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1

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5 December 2017

Mei Li

3

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Norbert B Ghyselinck

object named as

Norbert B Ghyselinck

series ordinal

6

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Pierre Chambon

series ordinal

7

object named as

Pierre Chambon

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5 December 2017

2

Arup Kumar Indra

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5 December 2017

4

Benoit Chapellier

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5 December 2017

Cécile Calleja

5

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PubMed ID

14631857

5 December 2017

language of work or name

English

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publication date

1 January 2003

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5 December 2017

Methods in Enzymology

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5 December 2017

364

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5 December 2017

379-408

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The nuclear receptor superfamily: the second decade

5 December 2017

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Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

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Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

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Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development

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7 January 2021

Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier

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Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription

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7 January 2021

Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

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Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton

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The secret life of the hair follicle

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The biology of hair follicles

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Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

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7 January 2021

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

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7 January 2021

Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

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7 January 2021

Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors

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7 January 2021

Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids

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7 January 2021

A transcriptional co-repressor that interacts with nuclear hormone receptors

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7 January 2021

A genetic dissection of the retinoid signalling pathway in the mouse

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7 January 2021

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

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7 January 2021

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

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Site- and time-specific gene targeting in the mouse

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Ligand-activated site-specific recombination in mice

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Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

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7 January 2021

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

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7 January 2021

Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled

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7 January 2021

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

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7 January 2021

Spatio-temporally controlled site-specific somatic mutagenesis in the mouse.

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7 January 2021

The pharmacology and clinical uses of tamoxifen

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Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy

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Generalized lacZ expression with the ROSA26 Cre reporter strain

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A transgenic mouse model with an inducible skin blistering disease phenotype

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Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

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7 January 2021

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

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Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase

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Dispase, a Neutral Protease From Bacillus Polymyxa, Is a Powerful Fibronectinase and Type IV Collagenase

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7 January 2021

Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.

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7 January 2021

Mouse models for the study of human hair loss

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The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE.

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7 January 2021

A conditional floxed (loxP-flanked) allele for the retinoic acid receptor alpha (RARalpha) gene

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Function of retinoic acid receptor gamma in the mouse

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The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

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High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice

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7 January 2021

Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin

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7 January 2021

A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RAR?) gene

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7 January 2021

Retinoic acid receptor gamma: specific immunodetection and phosphorylation

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Inducible site-directed recombination in mouse embryonic stem cells

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Temporally and spatially regulated somatic mutagenesis in mice

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7 January 2021

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

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7 January 2021

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

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Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice

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7 January 2021

The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets

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7 January 2021

Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity

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7 January 2021

Temporally controlled targeted somatic mutagenesis in the mouse brain

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7 January 2021

Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis

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7 January 2021

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

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7 January 2021

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

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7 January 2021

An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives

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7 January 2021

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

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7 January 2021

Inducible site-specific somatic mutagenesis in mouse hepatocytes

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Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis

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Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements

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A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

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7 January 2021

A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver

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7 January 2021

A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) gene

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Generation of a conditionally null allele ofhnf4?

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Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

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Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

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Generation and functional confirmation of a conditional null PPARgamma allele in mice.

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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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Identifiers

DOI

1 reference

5 December 2017

1 reference

PubMed ID

14631857