Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice (Q44675014)

5 December 2017

Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice (English)

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5 December 2017

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Runkuan Yang

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5 December 2017

Xiaonan Han

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2

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5 December 2017

Russell L Delude

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3

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5 December 2017

Mitchell P Fink

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4

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5 December 2017

1 November 2003

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5 December 2017

Translational Research

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5 December 2017

142

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5 December 2017

5

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5 December 2017

322-331

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Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial

5 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Increased plasma tumor necrosis factor in severe alcoholic hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Immunohistochemical detection of tumor necrosis factor-alpha, other cytokines and adhesion molecules in human livers with alcoholic hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

New insights into the the molecular mechanisms of alcoholic hepatitis: a potential role for NF-kappaB activation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Metallothionein-independent zinc protection from alcoholic liver injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Evidence for cytoprotection by prostaglandin E1 with normothermic hepatic ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Alcohol-induced generation of lipid peroxidation products in humans

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

The role of aldehyde oxidase in ethanol-induced hepatic lipid peroxidation in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Increased permeability of the gut to polyethylene glycol and dextran in rats fed alcohol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Acute exposure of small intestine to ethanol induces mucosal leakage and prostaglandin E2 synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Low-molecular-weight polyethylene glycol as a probe of gastrointestinal permeability after alcohol ingestion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Gut-associated lymphoid T cell suppression enhances bacterial translocation in alcohol and burn injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Chronic ethanol intake and burn injury: evidence for synergistic alteration in gut and immune integrity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Bacterial translocation and peptidoglycan translocation by acute ethanol administration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Binge drinking among US adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Screening of binge drinking among patients on an emergency surgical ward

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Effect of ethanol on B cell expression of major histocompatibility class II proteins in immunized mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Binge ethanol exposure decreases neurogenesis in adult rat hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Postbinge effects of acute alcohol intoxication on hepatic free radical formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Secretion of pyruvate. An antioxidant defense of mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species.

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

inferred from DOI database lookup

7 January 2021

based on heuristic

Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Pyruvate prevents ischemia-reperfusion mucosal injury of rat small intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Pyruvate inhibits hepatic ischemia-reperfusion injury in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Hydrogen peroxide-induced renal injury. A protective role for pyruvate in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Protection by pyruvate against transient forebrain ischemia in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Non-enzymic conversion of pyruvate in aqueous solution to 2,4-dihydroxy-2-methylglutaric acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Influence of pyruvic acid methyl ester on rat pancreatic islets. Effects on insulin secretion, phosphoinositide hydrolysis, and sensitization of the beta cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Spin trapping evidence for alcohol-associated oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Delivery of IkappaB superrepressor gene with adenovirus reduces early alcohol-induced liver injury in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Nitrosation and oxidation in the regulation of gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Prostaglandins protect human intestinal cells against ethanol injury by stabilizing microtubules: role of protein kinase C and enhanced calcium efflux

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2143%2803%2900138-0

10.1016/S0022-2143(03)00138-0

7 January 2021

Identifiers

DOI

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5 December 2017

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