mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior (Q44736089)

5 December 2017

mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior (English)

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5 December 2017

Pia Bäckström

1

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5 December 2017

Daniel Bachteler

2

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5 December 2017

Sabrina Koch

3

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5 December 2017

Petri Hyytiä

4

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5 December 2017

Rainer Spanagel

5

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5 December 2017

language of work or name

English

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publication date

1 May 2004

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5 December 2017

Neuropsychopharmacology

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5 December 2017

29

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5 December 2017

5

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5 December 2017

921-928

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300381

5 December 2017

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cites work

Reinstatement of ethanol seeking in rats: behavioral analysis.

1 reference

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Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat.

21 January 2018

1 reference

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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

21 January 2018

1 reference

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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

21 January 2018

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Selective involvement of mGlu1 receptors in corticostriatal LTD.

21 January 2018

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Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat.

21 January 2018

1 reference

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Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons

21 January 2018

1 reference

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Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice

21 January 2018

1 reference

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Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol seeking induced by priming injections of alcohol and exposure to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Neurobiology of relapse to alcohol in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Expression of glutamate receptor subunit/subtype messenger RNAS for NMDAR1, GLuR1, GLuR2 and mGLuR5 by accumbal projection neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist

21 January 2018

1 reference

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Effects of 5-HT(3) receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats.

21 January 2018

1 reference

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MPEP, a selective metabotropic glutamate receptor 5 antagonist, attenuates conditioned taste aversion in rats

21 January 2018

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Metabotropic glutamate receptors in brain function and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) blocks fear conditioning in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The reinstatement model of drug relapse: history, methodology and major findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

G protein-coupled receptor kinases regulate metabotropic glutamate receptor 5 function and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Pharmacological validation of a new animal model of alcoholism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

The role of glutamatergic neurotransmission in the pathophysiology of alcoholism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

A discriminative two-lever test of dizocilpine's ability to reinstate ethanol-seeking behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

Evidence for alcohol anti-craving properties of memantine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

7 January 2021

Additive effect of stress and drug cues on reinstatement of ethanol seeking: exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

7 January 2021

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

7 January 2021

Behavioral neurobiology of alcohol addiction: recent advances and challenges.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300381

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300381

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release_bd3fzgmykfdovchsts3moee2iu

5 December 2017

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Fatcat

https://api.fatcat.wiki/v0/release/bd3fzgmykfdovchsts3moee2iu

24 November 2022

mapped directly with Wikidata item

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