Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion (Q44754448)

6 December 2017

title

Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion (English)

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6 December 2017

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Shin-Rong Hwang

1

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6 December 2017

Christina Garza

2

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6 December 2017

Charles Mosier

3

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6 December 2017

Thomas Toneff

4

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6 December 2017

Eric Wunderlich

5

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6 December 2017

Paul Goldsmith

6

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6 December 2017

Vivian Hook

7

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6 December 2017

language of work or name

English

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publication date

23 January 2007

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Journal of Biological Chemistry

6 December 2017

published in

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6 December 2017

volume

282

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6 December 2017

issue

13

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6 December 2017

page(s)

9556-9563

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Precursor convertases in the secretory pathway, cytosol and extracellular milieu

6 December 2017

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Purification and characteristics of the candidate prohormone processing proteases PC2 and PC1/3 from bovine adrenal medulla chromaffin granules

21 January 2018

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Enkephalin convertase: purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules

21 January 2018

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Processing of enkephalin-containing peptides in isolated bovine adrenal chromaffin granules

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Distribution of enkephalin-containing peptides within bovine chromaffin granules

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Evidence for the proenkephalin processing enzyme prohormone thiol protease (PTP) as a multicatalytic cysteine protease complex: activation by glutathione localized to secretory vesicles

21 January 2018

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Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

21 January 2018

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21 January 2018

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Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines

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Chronic ethanol reduces nicotine-induced dopamine release in PC12 cells

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Proteolytic cleavage of chromogranin A (CgA) by plasmin. Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release

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Three distinct Ca(2+) influx pathways couple acetylcholine receptor activation to catecholamine secretion from PC12 cells.

21 January 2018

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Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance

21 January 2018

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Role of H+-ATPase-mediated acidification in sorting and release of the regulated secretory protein chromogranin A: evidence for a vesiculogenic function

21 January 2018

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PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells

21 January 2018

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Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells

21 January 2018

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Molecular cloning reveals isoforms of bovine alpha 1-antichymotrypsin

21 January 2018

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Formation of the catecholamine release-inhibitory peptide catestatin from chromogranin A. Determination of proteolytic cleavage sites in hormone storage granules

21 January 2018

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The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells

21 January 2018

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Tirilazad mesylate protects vitamins C and E in brain ischemia-reperfusion injury

21 January 2018

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Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathway

21 January 2018

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Biochemistry of the enkephalins and enkephalin-containing peptides

21 January 2018

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Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones

21 January 2018

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"Prohormone thiol protease" (PTP) processing of recombinant proenkephalin

21 January 2018

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Prohormone Thiol Protease and Enkephalin Precursor Processing: Cleavage at Dibasic and Monobasic Sites

21 January 2018

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Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules

21 January 2018

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An aminopeptidase activity in bovine pituitary secretory vesicles that cleaves the N-terminal arginine from beta-lipotropin60-65.

21 January 2018

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21 January 2018

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Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase

21 January 2018

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21 January 2018

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Identification of a 31,500 molecular weight islet cell protease as cathepsin B

21 January 2018

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Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

21 January 2018

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Cathepsin B is a prorenin processing enzyme

21 January 2018

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Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

21 January 2018

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The toxicity in vitro of beta-amyloid protein

21 January 2018

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Alzheimer's disease: perspectives for the new millennium

21 January 2018

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Golgi/granule processing of peptide hormone and neuropeptide precursors: A minireview

21 January 2018

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Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates

21 January 2018

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Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605510200

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6 December 2017

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