Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action (Q44805566)

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scientific article published on 18 March 2004

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English	Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action	scientific article published on 18 March 2004

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scholarly article

1 reference

Europe PubMed Central

6 December 2017

Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action (English)

1 reference

Europe PubMed Central

6 December 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Gerald I. Shulman

5

object named as

Gerald I Shulman

1 reference

Europe PubMed Central

6 December 2017

6

object named as

Jason K Kim

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Europe PubMed Central

6 December 2017

8

object named as

Barbara B Kahn

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Europe PubMed Central

6 December 2017

author name string

Janice M Zabolotny

1

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Europe PubMed Central

6 December 2017

Fawaz G Haj

2

1 reference

Europe PubMed Central

6 December 2017

Young-Bum Kim

3

1 reference

Europe PubMed Central

6 December 2017

Hyo-Jeong Kim

4

1 reference

Europe PubMed Central

6 December 2017

Benjamin G Neel

7

1 reference

Europe PubMed Central

6 December 2017

language of work or name

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publication date

18 March 2004

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Europe PubMed Central

6 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

6 December 2017

279

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Europe PubMed Central

6 December 2017

24844-24851

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Europe PubMed Central

6 December 2017

23

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Europe PubMed Central

6 December 2017

Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Coordinated action of protein tyrosine phosphatases in insulin signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Deficient LAR expression decreases basal forebrain cholinergic neuronal size and hippocampal cholinergic innervation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Dynamics of protein-tyrosine phosphatases in rat adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Increased abundance of specific skeletal muscle protein-tyrosine phosphatases in a genetic model of insulin-resistant obesity and diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Depot-specific variation in protein-tyrosine phosphatase activities in human omental and subcutaneous adipose tissue: a potential contribution to differential insulin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Altered basal and insulin-stimulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Marked impairment of protein tyrosine phosphatase 1B activity in adipose tissue of obese subjects with and without type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Suppression of insulin receptor activation by overexpression of the protein-tyrosine phosphatase LAR in hepatoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Functional association between the insulin receptor and the transmembrane protein-tyrosine phosphatase LAR in intact cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Cloning of a cDNA for a major human protein-tyrosine-phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. Application to hemophilia A.

1 reference

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21 January 2018

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda /zeta but not on glycogen synthase kinase-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

In vivo adenoviral delivery of recombinant human protein kinase C-zeta stimulates glucose transport activity in rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats.

1 reference

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21 January 2018

Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Impaired insulin signaling in the liver of transgenic rats with low circulating growth hormone levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

High-salt diet enhances insulin signaling and induces insulin resistance in Dahl salt-sensitive rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310688200

21 January 2018

Identifiers

10.1074/JBC.M310688200

1 reference

Europe PubMed Central

6 December 2017

1 reference

Europe PubMed Central

6 December 2017

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