Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis (Q44880264)

7 December 2017

Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis (English)

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7 December 2017

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Hannes Hentze

1

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7 December 2017

Markus Latta

2

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7 December 2017

Gerald Künstle

3

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7 December 2017

Saravanakumar Dhakshinamoorthy

4

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7 December 2017

Poh Yong Ng

5

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7 December 2017

Alan G Porter

6

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7 December 2017

Albrecht Wendel

7

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7 December 2017

language of work or name

English

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publication date

1 May 2004

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7 December 2017

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7 December 2017

39

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5

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7 December 2017

1311-1320

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7 December 2017

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Topoisomerase I inhibitors: review and update

21 January 2018

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Tumor cell death induced by topoisomerase-targeting drugs.

21 January 2018

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How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?

21 January 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: cell-free system studies

21 January 2018

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Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases

21 January 2018

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Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

21 January 2018

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Experimental hepatitis induced by D-galactosamine

21 January 2018

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Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

21 January 2018

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Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis

21 January 2018

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Non-specific effects of methyl ketone peptide inhibitors of caspases

21 January 2018

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

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Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

21 January 2018

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Tumor necrosis factor signaling.

21 January 2018

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TNF increases camptothecin-induced apoptosis by inhibition of NF-kappaB.

21 January 2018

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Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes

21 January 2018

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Role of nitric oxide in D-galactosamine-induced cell death and its protection by PGE1 in cultured hepatocytes.

21 January 2018

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Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling

21 January 2018

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c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

21 January 2018

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Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and

21 January 2018

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Unexpected hepatotoxicities in patients with non-Hodgkin's lymphoma treated with irinotecan (CPT-11) and etoposide

21 January 2018

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ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

21 January 2018

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Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan

21 January 2018

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Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

21 January 2018

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7 January 2021

Apoptosis induced by topoisomerase inhibitors

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7 January 2021

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

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7 January 2021

Galactosamine-induced sensitization to the lethal effects of endotoxin

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7 January 2021

Poisonous principles of mushrooms of the genus Amanita. Four-carbon amines acting on the central nervous system and cell-destroying cyclic peptides are produced

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7 January 2021

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

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7 January 2021

Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line

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7 January 2021

Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha

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7 January 2021

Activation of Programmed Cell Death by Recombinant Human Tumor Necrosis Factor Plus Topoisomerase II - Targeted Drugs in L929 Tumor Cells

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7 January 2021

Potentiation of topoisomerase I and II inhibitors cell killing by tumor necrosis factor: relationship to DNA strand breakage formation

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7 January 2021

Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

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7 January 2021

Subpopulations of rat hepatocytes separated by Percoll density-gradient centrifugation show characteristics consistent with different acinar locations

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7 January 2021

Identifiers

DOI

10.1002/HEP.20174

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7 December 2017

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