Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10. (Q44969105)

7 December 2017

Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10. (English)

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7 December 2017

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3

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7 December 2017

Niamh Murphy

1

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PubMed ID

24197756

7 December 2017

Belinda Grehan

series ordinal

2

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7 December 2017

7 November 2013

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7 December 2017

NeuroMolecular Medicine

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7 December 2017

16

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7 December 2017

1

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7 December 2017

205-215

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https://scigraph.springernature.com/pub.10.1007/s12017-013-8274-6

7 December 2017

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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

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TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation

21 January 2018

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Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid

21 January 2018

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

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Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome

21 January 2018

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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells

21 January 2018

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Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

21 January 2018

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

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Neuroinflammatory processes in Alzheimer's disease

21 January 2018

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The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release

21 January 2018

1 reference

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Anti-inflammatory activity of PYNOD and its mechanism in humans and mice

21 January 2018

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NLRP10 enhances Shigella-induced pro-inflammatory responses

21 January 2018

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CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4.

21 January 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

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The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells

21 January 2018

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Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway

21 January 2018

1 reference

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Evidence of a protective effect of phosphatidylserine-containing liposomes on lipopolysaccharide-induced impairment of long-term potentiation in the rat hippocampus

21 January 2018

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Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients.

21 January 2018

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Recognition of cytoplasmic RNA results in cathepsin-dependent inflammasome activation and apoptosis in human macrophages.

21 January 2018

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Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly

21 January 2018

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Interactions between APP secretases and inflammatory mediators

21 January 2018

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The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

21 January 2018

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PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.

21 January 2018

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Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24197756

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24197756

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24197756

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12017-013-8274-6

1 reference

7 December 2017

1 reference

PubMed ID

24197756