Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner (Q37415517)

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scientific article published on 12 August 2009

Language	Label	Description	Also known as
English	Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner	scientific article published on 12 August 2009

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

inflammasome complex

1 reference

based on heuristic

inferred from title

object named as

Jessica Chu

1

0 references

Gabriel Núñez

5

object named as

Gabriel Núñez

1 reference

Europe PubMed Central

20 August 2017

Russell D Salter

6

object named as

Russell D Salter

1 reference

Europe PubMed Central

20 August 2017

author name string

L Michael Thomas

2

1 reference

Europe PubMed Central

20 August 2017

Simon C Watkins

3

1 reference

Europe PubMed Central

20 August 2017

Luigi Franchi

4

1 reference

Europe PubMed Central

20 August 2017

publication date

12 August 2009

1 reference

Europe PubMed Central

20 August 2017

Journal of Leukocyte Biology

1 reference

Europe PubMed Central

20 August 2017

86

1 reference

Europe PubMed Central

20 August 2017

1227-1238

1 reference

Europe PubMed Central

20 August 2017

5

1 reference

Europe PubMed Central

20 August 2017

The inflammasomes: guardians of the body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774880

6 September 2017

Sensing pathogens and danger signals by the inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774880

6 September 2017

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774880

6 September 2017

IL-1, IL-18, and IL-33 families of cytokines

1 reference

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6 September 2017

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

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6 September 2017

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

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Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

1 reference

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Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation

1 reference

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Bacterial pore-forming toxins: the (w)hole story?

1 reference

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Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages

1 reference

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Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex

1 reference

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Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

1 reference

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6 September 2017

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

1 reference

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The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages

1 reference

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The P2X7 receptor: a key player in IL-1 processing and release

1 reference

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

1 reference

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Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

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Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

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Characterization of Listeria monocytogenes expressing anthrolysin O and phosphatidylinositol-specific phospholipase C from Bacillus anthracis

1 reference

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The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

1 reference

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Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists

1 reference

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Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes

1 reference

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Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

1 reference

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The family of thiol-activated, cholesterol-binding cytolysins

1 reference

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Thiol-activated cytolysins: structure, function and role in pathogenesis

1 reference

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6 September 2017

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

1 reference

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A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice

1 reference

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Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes

1 reference

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Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae

1 reference

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Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O.

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Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium

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Seeligeriolysin O, a protein toxin of Listeria seeligeri, stimulates macrophage cytokine production via Toll-like receptors in a profile different from that induced by other bacterial ligands.

1 reference

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Membrane damage and interleukin-1 production in murine macrophages exposed to listeriolysin O.

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Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

1 reference

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Mechanism of membrane damage by streptolysin-O.

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Isolation and culture of murine macrophages.

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26 June 2018

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26 June 2018

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Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675207

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1 reference

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Identifiers

10.1189/JLB.0309164

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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