Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse substantia nigra. (Q45030456)

8 December 2017

Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse substantia nigra (English)

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12 May 2020

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5

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12 May 2020

author name string

Renee M Miller

1

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12 May 2020

Linda M Callahan

2

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12 May 2020

Cindy Casaceli

3

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12 May 2020

Linlin Chen

4

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12 May 2020

Buena Chui

6

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12 May 2020

Tamma M Kaysser-Kranich

7

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12 May 2020

Timothy J Sendera

8

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12 May 2020

Chockalingam Palaniappan

9

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12 May 2020

Howard J Federoff

10

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12 May 2020

language of work or name

English

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publication date

1 August 2004

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8 December 2017

Journal of Neuroscience

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12 May 2020

volume

24

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12 May 2020

issue

34

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12 May 2020

page(s)

7445-7454

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Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss.

12 May 2020

cites work

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12 December 2020

Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles.

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12 December 2020

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

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12 December 2020

Cell cycle arrest and morphological alterations following microinjection of NIH3T3 cells with Pur alpha

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12 December 2020

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

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12 December 2020

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

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12 December 2020

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12 December 2020

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

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12 December 2020

Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse

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12 December 2020

Neural BC1 RNA associates with pur alpha, a single-stranded DNA and RNA binding protein, which is involved in the transcription of the BC1 RNA gene

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12 December 2020

The single-stranded DNA- and RNA-binding proteins pur alpha and pur beta link BC1 RNA to microtubules through binding to the dendrite-targeting RNA motifs

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12 December 2020

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

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12 December 2020

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

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12 December 2020

Effect of MPTP-induced denervation on basal ganglia GABA(B) receptors: correlation with dopamine concentrations and dopamine transporter

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12 December 2020

Significance analysis of microarrays applied to the ionizing radiation response

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12 December 2020

Experimental models of Parkinson's disease

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12 December 2020

Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology.

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12 December 2020

An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

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12 December 2020

1-Methyl-4-phenyl-pyridinium increases S-adenosyl-L-methionine dependent phospholipid methylation

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12 December 2020

Assessment of motor behavior using a video system and a clinical rating scale in parkinsonian monkeys lesioned by MPTP.

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12 December 2020

Induction of alpha-synuclein aggregation by intracellular nitrative insult.

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12 December 2020

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

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12 December 2020

Growth inhibition of glioblastoma cells by human Pur(alpha).

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12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

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12 December 2020

Trisialoganglioside GT1b induces in vivo degeneration of nigral dopaminergic neurons: role of microglia

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12 December 2020

Progressive reduction of synaptophysin message in single neurons in Alzheimer disease

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12 December 2020

Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons.

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12 December 2020

Constitutive Wee1 activity in adult brain neurons with M phase-type alterations in Alzheimer neurodegeneration.

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12 December 2020

Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta.

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12 December 2020

Summaries of Affymetrix GeneChip probe level data

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12 December 2020

Expression of S-100 protein is related to neuronal damage in MPTP-treated mice

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12 December 2020

Dependence on electron transport chain function and intracellular signaling of genomic responses in SH-SY5Y cells to the mitochondrial neurotoxin MPP+

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12 December 2020

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

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12 December 2020

Colocalization of Tau and Alpha-Synuclein Epitopes in Lewy Bodies

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12 December 2020

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

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12 December 2020

Convergent pathobiologic model of Parkinson's disease

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12 December 2020

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

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12 December 2020

Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

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12 December 2020

Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

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12 December 2020

Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

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12 December 2020

Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons

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12 December 2020

Fluoro-Gold's toxicity makes it inferior to True Blue for long-term studies of dorsal root ganglion neurons and motoneurons.

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12 December 2020

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

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12 December 2020

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

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12 December 2020

Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion

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12 December 2020

Inhibition of mitochondrial respiration by analogs of 4-phenylpyridine and 1-methyl-4-phenylpyridinium cation (MPP+), the neurotoxic metabolite of MPTP

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12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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12 December 2020

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.

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12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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12 December 2020

KIF3A is a new microtubule-based anterograde motor in the nerve axon

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12 December 2020

Functional studies on monoaminergic transmitter release in parkinsonism

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12 December 2020

TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons

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12 December 2020

Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.

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12 December 2020

Plasticity of the nigrostriatal system in MPTP-treated mice. A biochemical and morphological correlation.

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12 December 2020

mRNA expression of KIF1A, KIF1B, KIF2, KIF3A, KIF3B, KIF4, KIF5, and cytoplasmic dynein during axonal regeneration.

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12 December 2020

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

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12 December 2020

Induction of mitosis-related genes during dopamine-triggered apoptosis in sympathetic neurons

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12 December 2020

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

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12 December 2020

Differential display reveals transcriptional up-regulation of the motor molecules for both anterograde and retrograde axonal transport during nerve regeneration.

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12 December 2020

Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity

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12 December 2020

Identification of a cellular protein that binds to Tat-responsive element of TGF beta-1 promoter in glial cells

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12 December 2020

Adeno-associated virus gene transfer to mouse retina

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12 December 2020

Expression profiles of multiple genes in single neurons of Alzheimer's disease

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12 December 2020

Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells.

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12 December 2020

Alterations in Pur(alpha) levels and intracellular localization in the CV-1 cell cycle

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12 December 2020

Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease

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12 December 2020

The ubiquitin pathway in Parkinson's disease.

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12 December 2020

Nitric oxide in neurodegeneration.

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12 December 2020

10.1523/JNEUROSCI.4204-03.2004

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729635&resulttype=core&format=json

12 May 2020

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12 May 2020

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