Metabolic adaptations to chronic glucose infusion in rats (Q45045299)

8 December 2017

Metabolic adaptations to chronic glucose infusion in rats (English)

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8 December 2017

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B G Topp

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8 December 2017

M D McArthur

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2

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8 December 2017

D T Finegood

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3

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8 December 2017

2 September 2004

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8 December 2017

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8 December 2017

47

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8 December 2017

1602-1610

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8 December 2017

9

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https://scigraph.springernature.com/pub.10.1007/s00125-004-1493-5

8 December 2017

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12 December 2020

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

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12 December 2020

Effects of a 7-day infusion of glucose on insulin secretion in vivo and in vitro in ventromedial hypothalamic-lesioned obese rats.

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12 December 2020

Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions

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12 December 2020

Beta-cell adaptation and decompensation during the progression of diabetes.

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12 December 2020

Assessment of insulin sensitivity in vivo

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12 December 2020

A model of beta-cell mass, insulin, and glucose kinetics: pathways to diabetes.

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12 December 2020

Hyperinsulinaemia increases insulin action in vivo in white adipose tissue but not in muscles

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12 December 2020

Pancreatic beta-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement

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12 December 2020

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

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12 December 2020

A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development

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12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

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12 December 2020

Evolution of insulin secretory response to glucose by perifused islets from lean (FA/FA) rats chronically infused with glucose

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12 December 2020

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

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12 December 2020

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

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12 December 2020

Beta-cell deterioration--prospects for reversal or prevention

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12 December 2020

Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with beta-cell hyperproliferation in normoglycaemic 60 % pancreatectomy rats

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12 December 2020

Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression

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12 December 2020

The role of glucose in the in vitro regulation of cell cycle kinetics and proliferation of fetal pancreatic B-cells

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12 December 2020

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

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12 December 2020

Coupling of beta-cell desensitization by hyperglycemia to excessive stimulation and circulating insulin in glucose-infused rats

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12 December 2020

Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.

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12 December 2020

Insulin resistance in normal rats infused with glucose for 72 h.

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12 December 2020

beta-cell neogenesis during prolonged hyperglycemia in rats

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12 December 2020

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

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12 December 2020

Differential effects of prolonged hyperglycemia on in vivo and in vitro insulin secretion in rats

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12 December 2020

Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.

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12 December 2020

Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible?

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12 December 2020

Glucose toxicity: the implications of hyperglycemia in the pathophysiology of diabetes mellitus.

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12 December 2020

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

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12 December 2020

Natural history of beta-cell dysfunction in NIDDM.

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12 December 2020

Neogenesis vs. apoptosis As main components of pancreatic beta cell ass changes in glucose-infused normal and mildly diabetic adult rats

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12 December 2020

Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells

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12 December 2020

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

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12 December 2020

Impaired insulin secretion associated with near normoglycemia. Study in normal rats with 96-h in vivo glucose infusions

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12 December 2020

Clearance of apoptotic beta-cells is reduced in neonatal autoimmune diabetes-prone rats.

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12 December 2020

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

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12 December 2020

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes.

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12 December 2020

10.1007/S00125-004-1493-5

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8 December 2017

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