Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase (Q45057145)

9 December 2017

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase (English)

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9 December 2017

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Eric Spooner

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9 December 2017

Xin Ye

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9 December 2017

Jun Qin

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9 December 2017

Stephen J Elledge

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9 December 2017

Bruce E Clurman

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9 December 2017

J Wade Harper

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9 December 2017

language of work or name

English

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publication date

13 September 2004

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Journal of Biological Chemistry

9 December 2017

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9 December 2017

279

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48

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9 December 2017

50110-50119

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SCF and Cullin/Ring H2-based ubiquitin ligases

9 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Identification of a family of human F-box proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

A family of mammalian F-box proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

The Drosophila F box protein archipelago regulates dMyc protein levels in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Dual mode of degradation of Cdc25 A phosphatase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

Multisite phosphorylation and the countdown to S phase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

A phosphorylation-driven ubiquitination switch for cell-cycle control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409226200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409226200

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9 December 2017

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