The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. (Q45067620)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28920958%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells (English)

1 reference

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1

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Samie R. Jaffrey

19

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Michael G Kharas

20

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Christopher E Mason

1 reference

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Christopher Famulare

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30 March 2020

author name string

Brian F Pickering

2

1 reference

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30 March 2020

Yuanming Cheng

3

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30 March 2020

Sara Zaccara

4

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30 March 2020

Diu Nguyen

5

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30 March 2020

Gerard Minuesa

6

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30 March 2020

Timothy Chou

7

1 reference

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30 March 2020

Arthur Chow

8

1 reference

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30 March 2020

Yogesh Saletore

9

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30 March 2020

Matthew MacKay

10

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30 March 2020

Jessica Schulman

11

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30 March 2020

Minal Patel

13

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30 March 2020

Virginia M Klimek

14

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30 March 2020

Francine E Garrett-Bakelman

15

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30 March 2020

Ari Melnick

16

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30 March 2020

Martin Carroll

17

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30 March 2020

language of work or name

English

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publication date

18 September 2017

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30 March 2020

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volume

23

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issue

11

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30 March 2020

page(s)

1369-1376

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describes a project that uses

30 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5677536/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Reversible methylation of m6Am in the 5' cap controls mRNA stability

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Structural insights into the molecular mechanism of the m(6)A writer complex

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

m(6)A RNA methylation promotes XIST-mediated transcriptional repression

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Simple and inexpensive ribosome profiling analysis of mRNA translation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

STAR: ultrafast universal RNA-seq aligner

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

BCL-2 translation is mediated via internal ribosome entry during cell stress

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

MetaPlotR: a Perl/R pipeline for plotting metagenes of nucleotide modifications and other transcriptomic sites.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

Corrigendum: Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5677536

MEME SUITE: tools for motif discovery and searching

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4416

The absolute frequency of labeled N-6-methyladenosine in HeLa cell messenger RNA decreases with label time

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4416

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM.4416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28920958%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 March 2020

0 references

1 reference

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30 March 2020

PubMed publication ID

28920958

1 reference