Adjuvanticity of native and detoxified adenylate cyclase toxin of Bordetella pertussis towards co-administered antigens (Q45098739)

9 December 2017

title

Adjuvanticity of native and detoxified adenylate cyclase toxin of Bordetella pertussis towards co-administered antigens (English)

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9 December 2017

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Julia Macdonald-Fyall

1

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9 December 2017

Dorothy Xing

2

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9 December 2017

Michael Corbel

3

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9 December 2017

Susan Baillie

4

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9 December 2017

Roger Parton

5

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9 December 2017

John Coote

6

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9 December 2017

language of work or name

English

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publication date

1 October 2004

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9 December 2017

number of pages

12

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inferred from page(s)

published in

Vaccine

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9 December 2017

volume

22

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9 December 2017

issue

31-32

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9 December 2017

page(s)

4270-4281

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Acellular pertussis vaccines

9 December 2017

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Antibodies to Bordetella pertussis adenylate cyclase are produced in man during pertussis infection and after vaccination

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Protective activity of Bordetella adenylate cyclase-hemolysin against bacterial colonization

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Adjuvant and protective properties of native and recombinant Bordetella pertussis adenylate cyclase toxin preparations in mice

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Bordetella pertussis adenylate cyclase toxin: proCyaA and CyaC proteins synthesised separately in Escherichia coli produce active toxin in vitro.

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A direct pyrophosphatase-coupled assay provides new insights into the activation of the secreted adenylate cyclase from Bordetella pertussis by calmodulin

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Phagocytosed Bordetella pertussis fails to survive in human neutrophils

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A regulatory role for interleukin 4 in differential inflammatory responses in the lung following infection of mice primed with Th1- or Th2-inducing pertussis vaccines

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Neutralizing antibodies to adenylate cyclase toxin promote phagocytosis of Bordetella pertussis by human neutrophils

7 January 2021

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cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction

7 January 2021

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Protective immunity to Bordetella pertussis requires both B cells and CD4(+) T cells for key functions other than specific antibody production

7 January 2021

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Bordatella pertussis respiratory infection in children Is associated with preferential activation of Type 1 T helper cells

7 January 2021

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Effect of pertussis toxin on the induction of nitric oxide synthesis in murine macrophages and on protection in vivo

7 January 2021

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Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins

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Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28.

7 January 2021

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Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity

7 January 2021

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Native and Genetically Inactivated Pertussis Toxins Induce Human Dendritic Cell Maturation and Synergize with Lipopolysaccharide in Promoting T Helper Type 1 Responses

7 January 2021

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Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses

7 January 2021

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Pertussis toxin enhances Th1 responses by stimulation of dendritic cells

7 January 2021

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The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)

7 January 2021

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Immunity to Bordetella pertussis.

7 January 2021

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Investigation of cellular and humoral immune responses to whole cell and acellular pertussis vaccines

7 January 2021

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Th1/Th2 cell dichotomy in acquired immunity to Bordetella pertussis: variables in the in vivo priming and in vitro cytokine detection techniques affect the classification of T-cell subsets as Th1, Th2 or Th0

7 January 2021

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Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children

7 January 2021

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Role of adenylate cyclase-hemolysin in alveolar macrophage apoptosis during Bordetella pertussis infection in vivo.

7 January 2021

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7 January 2021

CyaC-mediated activation is important not only for toxic but also for protective activities of Bordetella pertussis adenylate cyclase-hemolysin.

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7 January 2021

Interleukin-12 is produced by macrophages in response to live or killed Bordetella pertussis and enhances the efficacy of an acellular pertussis vaccine by promoting induction of Th1 cells

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7 January 2021

A murine model in which protection correlates with pertussis vaccine efficacy in children reveals complementary roles for humoral and cell-mediated immunity in protection against Bordetella pertussis.

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7 January 2021

10.1016/J.VACCINE.2004.04.033

Identifiers

DOI

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9 December 2017

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