In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. (Q45187955)

10 December 2017

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. (English)

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10 December 2017

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5

K Barry Sharpless

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7

Hartmuth C Kolb

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Vani P Mocharla

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10 December 2017

Benoit Colasson

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Lac V Lee

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Stefanie Röper

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Chi-Huey Wong

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10 December 2017

language of work or name

English

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publication date

1 December 2004

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Angewandte Chemie International Edition

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5

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based on heuristic

inferred from page(s)

published in

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volume

44

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1

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116-120

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Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly

10 December 2017

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https://api.crossref.org/works/10.1002%2FANIE.200461580

In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A.

21 January 2018

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Drug discovery by dynamic combinatorial libraries

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Site-directed ligand discovery

21 January 2018

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In situ assembly of enzyme inhibitors using extended tethering

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.200461580

Dynamic combinatorial carbohydrate libraries: probing the binding site of the concanavalin A lectin

21 January 2018

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Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors

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Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly

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Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

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Multisubstrate adduct inhibitors of glycinamide ribonucleotide transformylase: Synthetic and enzyme-assembled

21 January 2018

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Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase

21 January 2018

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Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis.

21 January 2018

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DNA-templated dimerization of hairpin polyamides

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Carbonic anhydrase inhibitors

21 January 2018

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Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry

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Combinatorial computational method gives new picomolar ligands for a known enzyme

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

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Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

21 January 2018

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Self-assembling cytotoxins

21 January 2018

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9 October 2022

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Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants

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9 October 2022

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Dynamic combinatorial chemistry

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.200461580

Using an Enzyme's Active Site To Template Inhibitors This work was supported by the Centre National de la Recherche Scientifique and by the Ecole Polytechnique (predoctoral fellowship to R.N.). We thank Prof. Jean-Marie Lehn for stimulating discussi

1 reference

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Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

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Synergism through direct covalent bonding between agents: a strategy for rational design of chemotherapeutic combinations

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9 October 2022

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Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks

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In situ click chemistry: enzyme inhibitors made to their own specifications

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9 October 2022

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10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase

1 reference

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HYPOGLYCAEMIC AGENTS: VARIANTS OF TOLBUTAMIDE

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.200461580

Identifiers

DOI

10.1002/ANIE.200461580

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10 December 2017

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