A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis (Q45293309)

11 December 2017

title

A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis. (English)

1 reference

deleterious network hypothesis

11 December 2017

1 reference

1 reference

Ying W

1

1 reference

11 December 2017

publication date

1 October 1996

1 reference

11 December 2017

1 reference

11 December 2017

volume

47

1 reference

11 December 2017

issue

4

1 reference

11 December 2017

page(s)

307-313

1 reference

Bioenergetic and oxidative stress in neurodegenerative diseases

11 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Amyotrophic lateral sclerosis is a multifactorial disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Parkinson's disease: a test of the multifactorial etiologic hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Deleterious network hypothesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

NMDA-dependent superoxide production and neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Point mutations of mitochondrial genome in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Oxidative damage to protein in sporadic motor neuron disease spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Decrease in Cu/Zn- and Mn-superoxide dismutase activities in brain and spinal cord of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

The mechanism of glutamate-induced degeneration of cultured Huntington's disease and control fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Striatal deficiency of L-pyroglutamic acid in Huntington's disease is accompanied by increased plasma levels

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Marked increase in mitochondrial DNA deletion levels in the cerebral cortex of Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Oxygen radicals and neuropsychiatric illness. Some speculations

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Parkinson's disease and basal ganglia calcifications: prevalence and clinico-radiological correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Ion transport systems and Ca2+ regulation in aging neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Magnesium and Calcium Contents in CNS Tissues of Amyotrophic Lateral Sclerosis Patients from the Kii Peninsula, Japan

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Brainstem motoneuron pools that are selectively resistant in amyotrophic lateral sclerosis are preferentially enriched in parvalbumin: Evidence from monkey brainstem for a calcium-mediated mechanism in sporadic ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

A role for amplified protein kinase C activity in the pathogenesis of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

IgG from amyotrophic lateral sclerosis patients increases current through P-type calcium channels in mammalian cerebellar Purkinje cells and in isolated channel protein in lipid bilayer

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Striatal calcium channel antagonist receptors in Huntington's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Muscle lactate dehydrogenase activity is decreased in murine motor neuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

Calcium as sculptor and destroyer of neural circuitry

1 reference

https://api.crossref.org/works/10.1016%2FS0306-9877%2896%2990071-7

7 January 2021

10.1016/S0306-9877(96)90071-7

Identifiers

DOI

1 reference

11 December 2017

1 reference