Mutant huntingtin alters Tau phosphorylation and subcellular distribution (Q45301226)

11 December 2017

Mutant huntingtin alters Tau phosphorylation and subcellular distribution (English)

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11 December 2017

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11 December 2017

Laetitia Francelle

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Nicolas Sergeant

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Nicolas Sergeant

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Federico Herrera

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Federico Herrera

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Luc Buée

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Luc Buée

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author name string

Tiago Mendes

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11 December 2017

Marie Basquin

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11 December 2017

Hélène Obriot

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11 December 2017

Dominique Demeyer

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11 December 2017

Ellen Gerhardt

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11 December 2017

Tiago F Outeiro

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11 December 2017

20 August 2014

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11 December 2017

Human Molecular Genetics

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11 December 2017

24

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11 December 2017

76-85

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

11 December 2017

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Nuclear tau, a key player in neuronal DNA protection

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Deregulation of protein phosphatase 2A and hyperphosphorylation of τ protein following onset of diabetes in NOD mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Anesthesia, surgery and neurodegeneration. Preface.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

α-Synuclein modifies huntingtin aggregation in living cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Alzheimer-type lesions in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Association of corticobasal degeneration and Huntington's disease: can Tau aggregates protect Huntingtin toxicity?

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Kinase inhibitors modulate huntingtin cell localization and toxicity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Regional and cellular gene expression changes in human Huntington's disease brain

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Calcineurin inhibitors cause an acceleration of the neurological phenotype in a mouse transgenic for the human Huntington's disease mutation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Releasing the brake: restoring fast axonal transport in neurodegenerative disorders.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

21 January 2018

The many faces of tau

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Distinct annular oligomers captured along the assembly and disassembly pathways of transthyretin amyloid protofibrils

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Annular oligomeric amyloid intermediates observed by in situ atomic force microscopy

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Huntington's disease is a four-repeat tauopathy with tau nuclear rods.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Formation of toxic oligomeric alpha-synuclein species in living cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDU421

21 January 2018

Identifiers

DOI

10.1093/HMG/DDU421

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11 December 2017

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