Synthesis and evaluation of mimetics of UDP and UDP-alpha-D-galactose, dTDP and dTDP-alpha-D-glucose with monosaccharides replacing the key pyrophosphate unit. (Q45306229)

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English	Synthesis and evaluation of mimetics of UDP and UDP-alpha-D-galactose, dTDP and dTDP-alpha-D-glucose with monosaccharides replacing the key pyrophosphate unit.	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15750655%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Synthesis and evaluation of mimetics of UDP and UDP-alpha-D-galactose, dTDP and dTDP-alpha-D-glucose with monosaccharides replacing the key pyrophosphate unit (English)

1 reference

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9 January 2020

1

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9 January 2020

3

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9 January 2020

author name string

Robert J Young

2

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9 January 2020

publication date

21 February 2005

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9 January 2020

Organic and Biomolecular Chemistry

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9 January 2020

3

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9 January 2020

6

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9 January 2020

1109-1115

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9 January 2020

Formation of dTDP-rhamnose is essential for growth of mycobacteria

1 reference

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Inactivation of the mycobacterial rhamnosyltransferase, which is needed for the formation of the arabinogalactan-peptidoglycan linker, leads to irreversible loss of viability

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The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway

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The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB)

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Toward a structural understanding of the dehydratase mechanism

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Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis

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Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose

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Carbohydrate mimetics-based glycosyltransferase inhibitors

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Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis

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Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin

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The 3,4-O-Carbonate Protecting Group as a β-Directing Group in Rhamnopyranosylation in Both Homogeneous and Heterogeneous Glycosylations As Compared to the Chameleon-like 2,3-O-Carbonates

1 reference

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21 January 2018

Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar Typhimurium LT2.

1 reference

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21 January 2018

Design, synthesis and biological evaluation of hetaryl-nucleoside derivatives as inhibitors of chitin synthase

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Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase

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Identifiers

10.1039/B500418G

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15750655%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15750655%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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