PI3Kγ contributes to MEK1/2 activation in oxidative glutamate toxicity via PDK1. (Q45325618)

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5 March 2020

title

PI3Kγ contributes to MEK1/2 activation in oxidative glutamate toxicity via PDK1 (English)

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1

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author name string

Ki-Sun Kwon

series ordinal

2

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5 March 2020

Sung Sup Park

series ordinal

3

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language of work or name

English

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publication date

4 August 2013

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Journal of Neurochemistry

5 March 2020

published in

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volume

127

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issue

1

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page(s)

139-148

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Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target

5 March 2020

cites work

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21 January 2018

Excitotoxic cell death

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Chronic activation of ERK and neurodegenerative diseases.

21 January 2018

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Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

1 reference

Cellular survival: a play in three Akts

21 January 2018

1 reference

Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line

21 January 2018

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Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation

21 January 2018

1 reference

Extracellular hydrogen peroxide contributes to oxidative glutamate toxicity

21 January 2018

1 reference

Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection

21 January 2018

1 reference

Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke

21 January 2018

1 reference

Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium

21 January 2018

1 reference

Transient phosphatidylinositol 3-kinase inhibition protects immature primary cortical neurons from oxidative toxicity via suppression of extracellular signal-regulated kinase activation

21 January 2018

1 reference

Requirement for cGMP in nerve cell death caused by glutathione depletion

21 January 2018

1 reference

A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala

21 January 2018

1 reference

Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

1 reference

The specificity of neuroprotection by antioxidants

21 January 2018

1 reference

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

21 January 2018

1 reference

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway

21 January 2018

1 reference

Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons

21 January 2018

1 reference

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

21 January 2018

1 reference

Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures

21 January 2018

1 reference

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

21 January 2018

1 reference

The regulation of reactive oxygen species production during programmed cell death

21 January 2018

1 reference

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JNC.12364

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5 March 2020

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