Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway (Q47400542)

15 January 2018

title

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway (English)

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15 January 2018

author name string

Saori Sato

series ordinal

1

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15 January 2018

Naoya Fujita

series ordinal

2

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15 January 2018

Takashi Tsuruo

series ordinal

3

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15 January 2018

language of work or name

English

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publication date

2 June 2004

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15 January 2018

Journal of Biological Chemistry

number of pages

9

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based on heuristic

inferred from page(s)

published in

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volume

279

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15 January 2018

issue

32

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15 January 2018

page(s)

33759-33767

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The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

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MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling

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Modulation of Akt kinase activity by binding to Hsp90

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RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines

21 January 2018

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Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions

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Intracellular signalling: PDK1--a kinase at the hub of things

21 January 2018

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Different protein kinase C isoforms determine growth factor specificity in neuronal cells

21 January 2018

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Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

21 January 2018

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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

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Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro

21 January 2018

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MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

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A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

21 January 2018

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Role of ERas in promoting tumour-like properties in mouse embryonic stem cells

21 January 2018

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p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

21 January 2018

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The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M402055200

1 reference

15 January 2018

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15 January 2018