PARP inhibitor, olaparib ameliorates acute lung and kidney injury upon intratracheal administration of LPS in mice (Q45340890)

13 December 2017

PARP inhibitor, olaparib ameliorates acute lung and kidney injury upon intratracheal administration of LPS in mice (English)

1 reference

13 December 2017

1 reference

ChEBI release 2020-05-28

1 reference

Kunal Kapoor

1

1 reference

13 December 2017

Esha Singla

series ordinal

2

1 reference

13 December 2017

Bijayani Sahu

series ordinal

3

1 reference

13 December 2017

Amarjit S Naura

series ordinal

4

1 reference

13 December 2017

18 November 2014

1 reference

Molecular and Cellular Biochemistry

13 December 2017

1 reference

13 December 2017

400

1 reference

13 December 2017

1-2

1 reference

13 December 2017

153-162

1 reference

https://scigraph.springernature.com/pub.10.1007/s11010-014-2271-4

13 December 2017

0 references

cites work

The acute respiratory distress syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Incidence and outcomes of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Quality of life after acute respiratory distress syndrome: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Pathophysiology of acute lung injury and the acute respiratory distress syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Acute lung injury and the acute respiratory distress syndrome: a clinical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Endotoxin-induced lung injury in mice: structural, functional, and biochemical responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Animal models of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Differential effects of kidney-lung cross-talk during acute kidney injury and bacterial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Advances in critical care for the nephrologist: acute lung injury/ARDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase inhibitors: new pharmacological functions and potential clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

21 January 2018

PARP goes transcription

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Nuclear translocation of p65 NF-kappaB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Inhibition of poly(adenosine diphosphate-ribose) polymerase attenuates ventilator-induced lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Targeted therapy for cancer using PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Therapeutic potential of the poly(ADP-ribose) polymerase inhibitor rucaparib for the treatment of sporadic human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy Antigen Receptor for Chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Anticarcinogenic effects of hexaamminecobalt(III) chloride in mice initiated with diethylnitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

21 January 2018

Tissue sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Inhibitor of nuclear factor-κB, SN50, attenuates lipopolysaccharide-induced lung injury in an isolated and perfused rat lung model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-κB and p38 MAPK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Mechanism of neutrophil recruitment to the lung after pulmonary contusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Additives in intravenous anesthesia modulate pulmonary inflammation in a model of LPS-induced respiratory distress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Attenuation of lipopolysaccharide-induced acute lung injury by treatment with IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Models and mechanisms of acute lung injury caused by direct insults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Resolvin D1 attenuates lipopolysaccharide induced acute lung injury through CXCL-12/CXCR4 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

PARP-1 deficiency blocks IL-5 expression through calpain-dependent degradation of STAT-6 in a murine asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Post-allergen challenge inhibition of poly(ADP-ribose) polymerase harbors therapeutic potential for treatment of allergic airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Role of PARP on iNOS pathway during endotoxin-induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Protective effect of a novel, potent inhibitor of poly(adenosine 5'-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly (ADP-ribose) polymerase as a potential target for the treatment of acute renal injury caused by lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Signal transduction in inflammatory processes, current and future therapeutic targets: a mini review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

LPS preconditioning ameliorates intestinal injury in a rat model of hemorrhagic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2271-4

Cordycepin blocks lung injury-associated inflammation and promotes BRCA1-deficient breast cancer cell killing by effectively inhibiting PARP.

21 January 2018

1 reference

12 December 2020

Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death

1 reference

12 December 2020

Intratracheal aerosolization of endotoxin (LPS) in the rat: a comprehensive animal model to study adult (acute) respiratory distress syndrome.

1 reference

12 December 2020

Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice

1 reference

12 December 2020

Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia

1 reference

12 December 2020

A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation

1 reference

12 December 2020

Sustained lipopolysaccharide-induced lung inflammation in mice is attenuated by functional deficiency of the Fas/Fas ligand system

1 reference

12 December 2020

Pentoxifylline treatment attenuates pulmonary vasomotor dysfunction in acute lung injury

1 reference

12 December 2020

Microsomal lipid peroxidation

1 reference

12 December 2020

Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel FunctionIn VitroandIn Vivo

1 reference

12 December 2020

Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients

1 reference

12 December 2020

The relation between oxidative stress, inflammation, and neopterin in the paraquat-induced lung toxicity.

1 reference

12 December 2020

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

1 reference

12 December 2020

Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine

1 reference

12 December 2020

Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways.

1 reference

12 December 2020

Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes

1 reference

12 December 2020

[Prone position for the treatment of acute respiratory distress syndrome: a review of current literature]

1 reference

12 December 2020

10.1007/S11010-014-2271-4

Identifiers

DOI

1 reference

Dimensions Publication ID

13 December 2017

0 references

1 reference