Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. (Q45345920)

13 December 2017

title

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. (English)

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13 December 2017

Kei Miyano

1

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13 December 2017

Noriko Ueno

series ordinal

2

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13 December 2017

Ryu Takeya

series ordinal

3

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13 December 2017

Hideki Sumimoto

series ordinal

4

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13 December 2017

language of work or name

English

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publication date

8 June 2006

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Journal of Biological Chemistry

13 December 2017

published in

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13 December 2017

volume

281

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13 December 2017

issue

31

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13 December 2017

page(s)

21857-21868

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NADPH oxidases: not just for leukocytes anymore!

13 December 2017

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Electron transfer in the superoxide-generating NADPH oxidase complex reconstituted in vitro

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Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles. Evidence for an intermediate state of oxidase activation

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Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

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Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras

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Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production

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Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

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21 January 2018

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Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox

21 January 2018

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Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease

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156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox

21 January 2018

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21 January 2018

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Structure of the TPR domain of p67phox in complex with Rac.GTP

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Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system

21 January 2018

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Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function

21 January 2018

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A fusion protein between rac and p67phox (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components

21 January 2018

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Activation of the superoxide-generating NADPH oxidase by chimeric proteins consisting of segments of the cytosolic component p67(phox) and the small GTPase Rac1.

21 January 2018

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A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism

21 January 2018

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Cell transformation by the superoxide-generating oxidase Mox1

21 January 2018

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A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1

21 January 2018

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NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes

21 January 2018

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Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells

21 January 2018

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Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

21 January 2018

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Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Two novel proteins activate superoxide generation by the NADPH oxidase NOX1

21 January 2018

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Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells

21 January 2018

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21 January 2018

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Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch

21 January 2018

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The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators

21 January 2018

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

21 January 2018

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Regulation of H2O2 generation in thyroid cells does not involve Rac1 activation

21 January 2018

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Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

21 January 2018

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Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells

21 January 2018

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Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton

21 January 2018

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pEF-BOS, a powerful mammalian expression vector

21 January 2018

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Guanine nucleotides induce tyrosine phosphorylation and activation of the respiratory burst in neutrophils

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M513665200

Mechanism of activation of Pak1 kinase by membrane localization

21 January 2018

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Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox3 regulation by NOXO1, p47phox, and p67phox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox1-dependent reactive oxygen generation is regulated by Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

NADPH oxidase activity is independent of p47phox in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

21 January 2018

Identifiers

DOI

10.1074/JBC.M513665200

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13 December 2017

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