A three-dimensional model of the human immunodeficiency virus type 1 integration complex (Q45423719)

14 December 2017

title

A three-dimensional model of the human immunodeficiency virus type 1 integration complex (English)

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14 December 2017

1

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14 December 2017

3

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14 December 2017

Ian T Crosby

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14 December 2017

publication date

1 May 2005

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Journal of Computer - Aided Molecular Design

14 December 2017

published in

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14 December 2017

volume

19

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14 December 2017

issue

5

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14 December 2017

page(s)

301-317

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Brownian and essential dynamics studies of the HIV-1 integrase catalytic domain

14 December 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS10822-005-5256-2

Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation

21 January 2018

1 reference

12 December 2020

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

12 December 2020

AutoDocking dinucleotides to the HIV-1 integrase core domain: exploring possible binding sites for viral and genomic DNA.

1 reference

12 December 2020

Retroviral integrases and their cousins

1 reference

12 December 2020

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

1 reference

12 December 2020

Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis

1 reference

12 December 2020

The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

1 reference

12 December 2020

Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase

1 reference

12 December 2020

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

1 reference

12 December 2020

Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.

1 reference

12 December 2020

Refined solution structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase

1 reference

12 December 2020

Complementation between HIV integrase proteins mutated in different domains

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12 December 2020

Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

1 reference

12 December 2020

Solvent-accessible surfaces of proteins and nucleic acids

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12 December 2020

Comparative architecture of transposase and integrase complexes

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12 December 2020

Integration complexes derived from HIV vectors for rapid assays in vitro

1 reference

12 December 2020

Juxtaposition of two viral DNA ends in a bimolecular disintegration reaction mediated by multimers of human immunodeficiency virus type 1 or murine leukemia virus integrase.

1 reference

12 December 2020

The influence of DNA and nucleosome structure on integration events directed by HIV integrase

1 reference

12 December 2020

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity

1 reference

12 December 2020

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

1 reference

12 December 2020

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

1 reference

12 December 2020

Using HIV-1 sequence variability to explore virus biology

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12 December 2020

Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking.

1 reference

12 December 2020

Modeling HIV-1 integrase complexes based on their hydrodynamic properties

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12 December 2020

Retroviral DNA integration directed by HIV integration protein in vitro

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12 December 2020

Molecular biology. Transposase team puts a headlock on DNA.

1 reference

12 December 2020

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

1 reference

12 December 2020

Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins

1 reference

12 December 2020

Ordered water and ligand mobility in the HIV-1 integrase-5CITEP complex: a molecular dynamics study.

1 reference

12 December 2020

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

1 reference

12 December 2020

Mutational analysis of the integrase protein of human immunodeficiency virus type 2

1 reference

12 December 2020

In vitro assays for activities of retroviral integrase

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12 December 2020

Analysis of the full-length integrase–DNA complex by a modified approach for DNA docking

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12 December 2020

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

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12 December 2020

Mutational scan of the human immunodeficiency virus type 2 integrase protein

1 reference

12 December 2020

Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.

1 reference

12 December 2020

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

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12 December 2020

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

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12 December 2020

Structure and function of HIV-1 integrase

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12 December 2020

Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy

1 reference

12 December 2020

Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant

1 reference

12 December 2020

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1 reference

12 December 2020

Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

1 reference

12 December 2020

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

1 reference

12 December 2020

Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection

1 reference

12 December 2020

Tn5 as a model for understanding DNA transposition

1 reference

12 December 2020

Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistance

1 reference

12 December 2020

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

1 reference

12 December 2020

HIV-1 integrase: structural organization, conformational changes, and catalysis

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12 December 2020

Characterization of the minimal DNA-binding domain of the HIV integrase protein

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12 December 2020

Integrating DNA: transposases and retroviral integrases

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12 December 2020

Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase

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12 December 2020

In vivo analysis of retroviral integrase structure and function

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12 December 2020

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

1 reference

12 December 2020

Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core

1 reference

12 December 2020

Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

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12 December 2020

Role of DNA end distortion in catalysis by avian sarcoma virus integrase

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12 December 2020

Characterization of mutant HIV-1 integrase carrying amino acid changes in the catalytic domain

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12 December 2020

Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium

1 reference

12 December 2020

A metal-induced conformational change and activation of HIV-1 integrase

1 reference

12 December 2020

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

1 reference

12 December 2020

Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor

1 reference

12 December 2020

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

12 December 2020

Target-sequence preferences of HIV-1 integration complexes in vitro.

1 reference

12 December 2020

The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity

1 reference

12 December 2020

Solution structure of the DNA binding domain of HIV-1 integrase

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12 December 2020

Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.

1 reference

12 December 2020

Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro

1 reference

12 December 2020

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

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12 December 2020

Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration

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12 December 2020

Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase.

1 reference

12 December 2020

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

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12 December 2020

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

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12 December 2020

Role of the nonspecific DNA-binding region and alpha helices within the core domain of retroviral integrase in selecting target DNA sites for integration

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12 December 2020

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

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12 December 2020

Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

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12 December 2020

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

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12 December 2020

The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

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12 December 2020

Recombining the structures of HIV integrase, RuvC and RNase H.

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12 December 2020

Retroviral DNA integration.

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12 December 2020

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

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12 December 2020

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

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12 December 2020

Protein folds and families: sequence and structure alignments

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12 December 2020

The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9-A resolution

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12 December 2020

Mapping DNA-binding sites of HIV-1 integrase by protein footprinting

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12 December 2020

Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

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12 December 2020

Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis

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12 December 2020

Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

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12 December 2020

Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

1 reference

12 December 2020

Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

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12 December 2020

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

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12 December 2020

Molecular dynamics studies on the HIV-1 integrase catalytic domain

1 reference

12 December 2020

Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

1 reference

12 December 2020

Functional oligomeric state of avian sarcoma virus integrase

1 reference

12 December 2020

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

1 reference

12 December 2020

10.1007/S10822-005-5256-2

Identifiers

DOI

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journals/jcamd/WielensCC05

14 December 2017

DBLP publication ID

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DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

1001460474

0 references

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