The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response (Q45510140)

14 December 2017

The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response (English)

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14 December 2017

vaccinia virus

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Teresa Brandt

1

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14 December 2017

Michael C Heck

2

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14 December 2017

Sangeetha Vijaysri

3

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14 December 2017

Garilyn M Jentarra

4

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14 December 2017

Jason M Cameron

5

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14 December 2017

Bertram L Jacobs

6

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14 December 2017

language of work or name

English

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publication date

1 March 2005

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14 December 2017

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14 December 2017

333

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14 December 2017

2

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14 December 2017

263-270

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Generation and use of recombinant reporter viruses for study of herpes simplex virus infections in vivo

14 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Identification of a conserved motif that is necessary for binding of the vaccinia virus E3L gene products to double-stranded RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

A role for Z-DNA binding in vaccinia virus pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Evidence that vaccinia virulence factor E3L binds to Z-DNA in vivo: Implications for development of a therapy for poxvirus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Inhibition of PKR by vaccinia virus: role of the N- and C-terminal domains of E3L.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Induction of potent humoral and cell-mediated immune responses by attenuated vaccinia virus vectors with deleted serpin genes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Complementation of vaccinia virus deleted of the E3L gene by mutants of E3L.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Vaccinia virus vectors with an inactivated gamma interferon receptor homolog gene (B8R) are attenuated In vivo without a concomitant reduction in immunogenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Biological characterization of recombinant vaccinia viruses in mice infected by the respiratory route

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

Molecular attenuation of vaccinia virus: mutant generation and animal characterization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2005.01.006

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14 December 2017

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