AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells (Q45858441)

17 December 2017

title

AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells (English)

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17 December 2017

main subject

retinal ganglion cell

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Leaver SG

1

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17 December 2017

Cui Q

2

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17 December 2017

Plant GW

3

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17 December 2017

Arulpragasam A

4

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17 December 2017

Hisheh S

5

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17 December 2017

Verhaagen J

6

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17 December 2017

Harvey AR

7

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17 December 2017

publication date

18 May 2006

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

13

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17 December 2017

issue

18

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17 December 2017

page(s)

1328-1341

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302791

exact match

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cites work

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Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo.

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Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells

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Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

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Synergistic effect of Nogo-neutralizing antibody IN-1 and ciliary neurotrophic factor on axonal regeneration in adult rodent visual systems

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Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.

21 January 2018

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Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats.

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Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy.

21 January 2018

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21 January 2018

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Adeno-associated virus-vectored gene therapy for retinal disease

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Gene delivery to the eye using adeno-associated viral vectors

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Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury

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Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity

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Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transfer

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Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons.

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Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma

21 January 2018

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EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans

21 January 2018

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IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

21 January 2018

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AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse

21 January 2018

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21 January 2018

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Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

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Rate of regrowth of damaged retinal ganglion cell axons regenerating in a peripheral nerve graft in adult hamsters.

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21 January 2018

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Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

21 January 2018

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Housekeeping gene expression during fetal brain development in the rat-validation by semi-quantitative RT-PCR.

21 January 2018

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Delivery of ciliary neurotrophic factor via lentiviral-mediated transfer protects axotomized retinal ganglion cells for an extended period of time

21 January 2018

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Ciliary neurotrophic factor protects retinal ganglion cells from axotomy-induced apoptosis via modulation of retinal glia in vivo

21 January 2018

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B-50/GAP43 Expression Correlates with Process Outgrowth in the Embryonic Mouse Nervous System

21 January 2018

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Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

21 January 2018

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Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells

21 January 2018

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The neurotrophins and CNTF: two families of collaborative neurotrophic factors

21 January 2018

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Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation

21 January 2018

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Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2Rd2/Rd2 model of retinal degeneration

21 January 2018

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Retinal ganglion cells lose trophic responsiveness after axotomy

21 January 2018

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Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.

21 January 2018

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Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

21 January 2018

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Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury.

21 January 2018

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Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system

21 January 2018

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Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.

21 January 2018

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7 January 2021

Lens injury stimulates axon regeneration in the mature rat optic nerve

1 reference

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Macrophage-derived factors stimulate optic nerve regeneration.

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Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury

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Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

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Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo.

1 reference

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Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

1 reference

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Brain-derived neurotrophic factor and neurotrophin-4/5 stimulate growth of axonal branches from regenerating retinal ganglion cells

1 reference

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Neurobiology of the regenerating retina and its functional reconnection with the brain by means of peripheral nerve transplants in adult rats.

1 reference

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Adenovirus-mediated expression of ciliary neurotrophic factor (CNTF) rescues axotomized rat retinal ganglion cells but does not support axonal regeneration in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

Brain-derived neurotrophic factor (BDNF) prevents lesion-induced axonal die-back in young rat optic nerve

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

BDNF modulates, but does not mediate, activity-dependent branching and remodeling of optic axon arbors in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302791

7 January 2021

Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302791

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017