Zinc supplementation augments TGF-β1-dependent regulatory T cell induction (Q45861386)

17 December 2017

title

Zinc supplementation augments TGF-β1-dependent regulatory T cell induction (English)

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17 December 2017

Lothar Rink

4

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Ralf Weiskirchen

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Ralf Weiskirchen

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3

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author name string

Martina Maywald

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1

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17 December 2017

Steffen K Meurer

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2

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17 December 2017

publication date

29 October 2016

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17 December 2017

Molecular Nutrition and Food Research

published in

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17 December 2017

volume

61

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17 December 2017

issue

3

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17 December 2017

Development and maintenance of regulatory T cells

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STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

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Zinc signals promote IL-2-dependent proliferation of T cells

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Chronic zinc deficiency in mice disrupted T cell lymphopoiesis and erythropoiesis while B cell lymphopoiesis and myelopoiesis were maintained

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Zinc chloride-mediated reduction of apoptosis as an adjunct immunosuppressive modality in cardiac transplantation

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Zinc enhances the number of regulatory T cells in allergen-stimulated cells from atopic subjects.

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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

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TGF-beta: a master of all T cell trades

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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

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The biochemical effects of extracellular Zn(2+) and other metal ions are severely affected by their speciation in cell culture media.

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Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

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Regulatory T cells and immune tolerance

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Zinc in pharmacological doses suppresses allogeneic reaction without affecting the antigenic response

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TGFbeta signalling in control of T-cell-mediated self-reactivity

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

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Phosphorylation of the lymphoid cell kinase p56lck is stimulated by micromolar concentrations of Zn2+.

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A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of Lck

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Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling.

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Signals and pathways controlling regulatory T cells

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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

21 January 2018

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Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization

21 January 2018

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Monomeric type I and type III transforming growth factor-β receptors and their dimerization revealed by single-molecule imaging

21 January 2018

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TbetaRI/Alk5-independent TbetaRII signaling to ERK1/2 in human skin cells according to distinct levels of TbetaRII expression

21 January 2018

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Zinc oxide influences mitogen-activated protein kinase and TGF-β1 signaling pathways, and enhances intestinal barrier integrity in weaned pigs.

21 January 2018

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Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

21 January 2018

Identifiers

DOI

10.1002/MNFR.201600493

1 reference

17 December 2017

1 reference

17 December 2017