Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. (Q45879717)

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5 January 2020

title

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS (English)

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amyotrophic lateral sclerosis

5 January 2020

main subject

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7

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Edward M. Conway

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Erik Storkebaum

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Bart P. Rutten

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Ludo Van Den Bosch

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Lieve Moons

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Peter Carmeliet

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Sabine Wyns

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19

Désiré Collen

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17

Wim Robberecht

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9

Wing Yan Man

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2

Diether Lambrechts

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author name string

Mieke Dewerchin

3

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Maria-Paz Moreno-Murciano

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Saskia Appelmans

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Hideyasu Oh

6

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Maria De Mol

10

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David Manka

12

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Kristel Vermeulen

13

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Nico Mertens

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Christoph Schmitz

16

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language of work or name

English

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publication date

28 November 2004

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5 January 2020

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volume

8

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issue

1

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5 January 2020

page(s)

85-92

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Recent advances in amyotrophic lateral sclerosis research

5 January 2020

cites work

1 reference

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

The biology of VEGF and its receptors

21 January 2018

1 reference

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

21 January 2018

1 reference

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

21 January 2018

1 reference

VEGF: a critical player in neurodegeneration

21 January 2018

1 reference

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

21 January 2018

1 reference

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

21 January 2018

1 reference

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

1 reference

Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1(G93A G1H) mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo

21 January 2018

1 reference

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

21 January 2018

1 reference

Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies

21 January 2018

1 reference

Location, location, location: a spatial view of neurotrophin signal transduction

21 January 2018

1 reference

Anterograde axonal transport of glial cell line-derived neurotrophic factor and its receptors in rat hypoglossal nerve

21 January 2018

1 reference

Mutant mouse models of insulin-like growth factor actions in the central nervous system

21 January 2018

1 reference

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

21 January 2018

1 reference

The GDNF family: signalling, biological functions and therapeutic value

21 January 2018

1 reference

Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene

21 January 2018

1 reference

IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment

21 January 2018

1 reference

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

21 January 2018

1 reference

Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4.

21 January 2018

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Amyotrophic lateral sclerosis: pathogenesis

21 January 2018

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7 January 2021

Of mice and men: reconciling preclinical ALS mouse studies and human clinical trials

1 reference

7 January 2021

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

1 reference

7 January 2021

The effect of leukaemia inhibitory factor on SOD1 G93A murine amyotrophic lateral sclerosis

1 reference

7 January 2021

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

1 reference

7 January 2021

Anterograde transport of tumor necrosis factor-alpha in the intact and injured rat sciatic nerve

1 reference

7 January 2021

Investigation of a null mutation of the CNTF gene in familial amyotrophic lateral sclerosis

1 reference

7 January 2021